Question

Difficulty: MediumIdentifying Trends and Relationships

Biophysicists conducted an experiment measuring the action potential conduction velocity (vv, in m/s\text{m/s}) in unmyelinated giant nerve fibers as a function of fiber diameter (dd, in μm\mu\text{m}) at a constant temperature of 20C20^\circ\text{C}. The recorded data is presented in Table 1.

Fiber Diameter (dd, μm\mu\text{m})Conduction Velocity (vv, m/s\text{m/s})
1005.0
2008.0
40014.0
60018.0
90021.0

Based on Table 1, what is the average rate of change in conduction velocity, in m/s\text{m/s} per 100μm100\,\mu\text{m} increase in fiber diameter, over the interval from d=200μmd = 200\,\mu\text{m} to d=600μmd = 600\,\mu\text{m}?

Answer: 2.5 m/s per 100 µm

Answer

The average rate of change in conduction velocity over the specified interval is 2.5m/s per 100μm2.5\,\text{m/s per }100\,\mu\text{m} increase in fiber diameter.
To find the average rate of change in conduction velocity per 100μm100\,\mu\text{m} increase in fiber diameter between d=200μmd = 200\,\mu\text{m} and d=600μmd = 600\,\mu\text{m}, subtract the initial velocity (8.0m/s8.0\,\text{m/s}) from the final velocity (18.0m/s18.0\,\text{m/s}) to get Δv=10.0m/s\Delta v = 10.0\,\text{m/s}. Divide by the change in diameter Δd=600200=400μm\Delta d = 600 - 200 = 400\,\mu\text{m} to obtain 0.025m/s per μm0.025\,\text{m/s per }\mu\text{m}. Multiplying by 100100 yields 2.5m/s per 100μm2.5\,\text{m/s per }100\,\mu\text{m}.

Step-by-Step Solution

1
Locate data points for d=200μmd = 200\,\mu\text{m} and d=600μmd = 600\,\mu\text{m} in Table 1.
At d=200μmd = 200\,\mu\text{m}, v=8.0m/sv = 8.0\,\text{m/s}. At d=600μmd = 600\,\mu\text{m}, v=18.0m/sv = 18.0\,\text{m/s}.
These data points define the boundaries of the interval specified in the question.
2
Calculate the overall changes in velocity (Δv\Delta v) and diameter (Δd\Delta d).
Δv=18.08.0=10.0m/s\Delta v = 18.0 - 8.0 = 10.0\,\text{m/s} and Δd=600200=400μm\Delta d = 600 - 200 = 400\,\mu\text{m}.
Calculating the rate of change requires dividing the change in the dependent variable by the change in the independent variable.
3
Scale the rate of change to a 100μm100\,\mu\text{m} diameter interval.
10.0m/s400μm×100μm=2.5m/s per 100μm\frac{10.0\,\text{m/s}}{400\,\mu\text{m}} \times 100\,\mu\text{m} = 2.5\,\text{m/s per }100\,\mu\text{m}.
The question asks specifically for the rate per 100μm100\,\mu\text{m} increase in diameter.

Key Concept

Calculating average rate of change and trend slopes from quantitative scientific data tables.
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