The paragraphs below are from a draft of an essay about the history of microbiology. To make the essay most logical and cohesive, in what order should the paragraphs be placed?
- 1[Paragraph 2] In the late nineteenth century, the search for a reliable solid culture medium presented a formidable obstacle in the field of microbiology. The pioneering researcher Robert Koch found potato slices to be nutrient-poor and structurally inconsistent, while gelatin, though nutrient-rich, consistently liquefied at the warm temperatures required to incubate human pathogens (typically above ).
- 2[Paragraph 3] Observing these laboratory struggles, Fanny Hesse, the wife of Koch’s assistant Walther Hesse, suggested a culinary alternative: agar-agar. She had used the seaweed-derived extract for years to keep her puddings and jellies from melting during hot summer days.
- 3[Paragraph 4] This simple recommendation transformed the research environment. Koch immediately integrated the new medium into his experiments, finding that it remained solid at temperatures well above and, crucially, was resistant to degradation by bacterial enzymes.
- 4[Paragraph 1] The subsequent transition to agar-agar enabled the isolation of the tuberculosis bacillus, a breakthrough that solidified Koch’s place in medical history. Today, this gelatinous substance remains the global standard for bacterial cultivation, a testament to the unexpected intersection of domestic culinary practice and laboratory science.
Answer
The correct order of the paragraphs is Paragraph 2, followed by Paragraph 3, then Paragraph 4, and finally Paragraph 1.
The correct order is Paragraph 2, Paragraph 3, Paragraph 4, Paragraph 1. Paragraph 2 introduces the historical setting and the challenge of finding a solid bacterial culture medium. Paragraph 3 follows logically by referencing 'these laboratory struggles' and proposing agar-agar as a solution. Paragraph 4 details the integration of 'this simple recommendation' and its immediate success in the lab. Finally, Paragraph 1 describes 'the subsequent transition' to agar-agar as a historical breakthrough and concludes by referencing its modern usage.
Step-by-Step Solution
Key Concept
Paragraph Reordering and Placement