While the ABO blood group system in human populations is governed by three multiple allele… — JAMB UTME

While the ABO blood group system in human populations is governed by three multiple alleles ( $I^A$ , $I^B$ , and $i$ ), any given diploid individual can inherit a maximum of two alleles, with $I^A$ and $I^B$ exhibiting codominance with each other while both display complete dominance over the allele $i$ .

Answer: Answer

Answer

True

The statement accurately distinguishes between population-level multiple alleles and individual diploid genetic constitution, while correctly identifying the codominant relationship between

I^A

and

I^B

alongside their complete dominance over the recessive

i

allele.

Step-by-Step Solution

Analyze allele distribution in populations versus diploid individuals.

Multiple alleles refer to the presence of more than two allele options in a population gene pool (

I^A

I^B

i

), but diploid organisms possess only two locus copies (one maternal, one paternal).

Meiotic segregation and diploid chromosome organization restrict an individual to possessing a maximum of two alleles for any autosomal gene.

Examine the phenotypic expression pattern of heterozygous genotype

I^A I^B

Both antigen A and antigen B are independently and fully expressed on red blood cell surfaces, defining codominance.

Codominance occurs when neither allele masks the other, leading to simultaneous, distinct expression of both allele products.

Evaluate the interaction between alleles

I^A

I^B

and allele

i

Genotypes

I^A i

and

I^B i

result in blood group A and blood group B phenotypes respectively, as allele

i

produces a non-functional enzyme.

Allele

i

is recessive, so

I^A

and

I^B

exhibit complete dominance over

i

Key Concept

Multiple Alleles and Codominance in ABO Blood Groups

Estimated Time:1m 30s

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