Question

Difficulty: MediumPharmacological and Parenteral Therapies

A healthcare provider prescribes a continuous intravenous dopamine infusion at 5 mcg/kg/min5\text{ mcg/kg/min} to support the blood pressure of a client in cardiogenic shock. The client's body weight is recorded as 176 lb176\text{ lb}. The medication is supplied in an intravenous bag containing 400 mg400\text{ mg} of dopamine mixed in 250 mL250\text{ mL} of 5% dextrose in water (D5W). At what rate, in mL/hr\text{mL/hr}, should the infusion pump be programmed? (Record your answer as a whole number)

Answer: 15 mL/hr

Answer

15
The correct rate of 15 mL/hr is achieved by converting the client's weight to kg (80 kg), calculating the hourly dose in mg (24 mg/hr), and dividing by the IV bag's concentration (1.6 mg/mL).

Step-by-Step Solution

1
Convert the client's weight from pounds to kilograms.
176 lb÷2.2=80 kg176\text{ lb} \div 2.2 = 80\text{ kg}
The prescribed dose is based on the client's weight in kilograms.
2
Calculate the required dose per minute.
5 mcg/kg/min×80 kg=400 mcg/min5\text{ mcg/kg/min} \times 80\text{ kg} = 400\text{ mcg/min}
To determine the total micrograms of medication the client needs every minute.
3
Calculate the total dose required per hour.
400 mcg/min×60 min/hr=24,000 mcg/hr400\text{ mcg/min} \times 60\text{ min/hr} = 24,000\text{ mcg/hr}
Infusion pumps are programmed in fluid volume per hour, so the dose must be scaled to an hourly rate.
4
Convert the hourly dose from micrograms to milligrams.
24,000 mcg÷1000=24 mg/hr24,000\text{ mcg} \div 1000 = 24\text{ mg/hr}
The supplied medication in the IV bag is measured in milligrams.
5
Determine the medication concentration in the supplied IV bag.
400 mg÷250 mL=1.6 mg/mL400\text{ mg} \div 250\text{ mL} = 1.6\text{ mg/mL}
To know how many milligrams of dopamine are contained in each milliliter of the solution.
6
Calculate the required volume to be infused per hour.
24 mg/hr÷1.6 mg/mL=15 mL/hr24\text{ mg/hr} \div 1.6\text{ mg/mL} = 15\text{ mL/hr}
To determine the final setting for the infusion pump in mL/hr.

Key Concept

Weight-based intravenous continuous infusion rate calculation
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