Question

Difficulty: MediumPharmacological and Parenteral Therapies

A nurse is preparing to administer a prescribed unit of packed red blood cells (PRBCs) to a client with severe anemia. In what order should the nurse perform the following actions? Arrange the steps in the correct chronological sequence.

  1. 1Verify the provider's prescription, confirm informed consent is signed, and assess baseline vital signs.
  2. 2Retrieve the unit of packed red blood cells from the blood bank.
  3. 3Verify the blood product, blood type, and client identity with a second registered nurse at the bedside.
  4. 4Spike the blood bag and initiate the transfusion at a slow rate of 2 mL/min.
  5. 5Remain with the client and reassess vital signs 15 minutes after the transfusion begins.

Answer

The correct chronological sequence is: Verify prescription/consent/vitals, Retrieve blood from the blood bank, Verify with a second nurse at the bedside, Initiate the transfusion slowly, and Remain with the client for 15 minutes to reassess vital signs.
Safe administration of packed red blood cells requires strict adherence to chronological safety checkpoints. First, the nurse must ensure the client is ready (consent, baseline vitals, patent IV) before retrieving the blood, as it expires in 30 minutes at room temperature. Once retrieved, two-nurse verification must occur at the bedside to prevent ABO incompatibility. The transfusion is initiated slowly to mitigate the severity of any potential reaction, and the nurse must remain with the client for the first 15 minutes, as this is when life-threatening reactions are most likely to occur.

Step-by-Step Solution

1
Verify the provider's prescription, confirm informed consent is signed, and assess baseline vital signs.
Ensures legal readiness and establishes a baseline to monitor for reactions.
Blood must be initiated within 30 minutes of leaving the blood bank. Gathering baseline vital signs first ensures the client does not have a fever that might delay the transfusion.
2
Retrieve the unit of packed red blood cells from the blood bank.
The specific unit of PRBCs is brought to the nursing unit.
This is done only after confirming the client is clinically ready and IV access is patent.
3
Verify the blood product, blood type, and client identity with a second registered nurse at the bedside.
Confirms an exact match between the client's identification band, the blood type, and the unit number.
Prevents fatal ABO incompatibility reactions. This must be done directly at the bedside, not at the nurses' station.
4
Spike the blood bag and initiate the transfusion at a slow rate of 2 mL/min.
The blood transfusion begins.
A slow initial rate limits the volume of blood infused, minimizing the severity of a reaction if one occurs.
5
Remain with the client and reassess vital signs 15 minutes after the transfusion begins.
The client is closely monitored during the most critical period.
Most severe transfusion reactions (e.g., acute hemolytic or anaphylactic) happen within the first 15 minutes or first 50 mL of blood.

Key Concept

Blood Transfusion Administration Safety and Sequencing
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