Question

Difficulty: MediumPharmacological and Parenteral Therapies

A nurse is preparing to administer furosemide 80 mg80 \text{ mg} intravenous (IV) push to a client experiencing acute pulmonary edema. The medication is available in a vial labeled 10 mg/mL10 \text{ mg/mL}. Which of the following is the most appropriate action for the nurse to take?

  1. Administer 8 mL8 \text{ mL} of the medication at a rate of 2 mL2 \text{ mL} per minute.Answer
  2. B
    Administer 8 mL8 \text{ mL} of the medication at a calculated rate of 4 mL4 \text{ mL} per minute.
  3. C
    Administer the medication through the nearest Y-site without pausing to verify compatibility with the continuous infusion.
  4. D
    Administer the dose rapidly over 30 to 60 seconds to prioritize the immediate resolution of respiratory distress.

Answer

The nurse should administer 8 mL8 \text{ mL} of the medication at a rate of 2 mL2 \text{ mL} per minute.
The correct action involves accurately calculating both the volume to administer and the safe rate of administration. Furosemide is available at 10 mg/mL10 \text{ mg/mL}, so an 80 mg80 \text{ mg} dose requires 8 mL8 \text{ mL}. To prevent ototoxicity, IV furosemide should be administered no faster than 20 mg20 \text{ mg} per minute. An 80 mg80 \text{ mg} dose must be pushed over at least 4 minutes (80÷20=480 \div 20 = 4). Administering 8 mL8 \text{ mL} over 4 minutes equates to a safe and calculated rate of 2 mL2 \text{ mL} per minute.

Step-by-Step Solution

1
Calculate the required volume of the medication.
80 mg10 mg/mL=8 mL \frac{80 \text{ mg}}{10 \text{ mg/mL}} = 8 \text{ mL}
To ensure the correct dose is drawn from the vial.
2
Determine the minimum safe administration time.
80 mg20 mg/min=4 minutes \frac{80 \text{ mg}}{20 \text{ mg/min}} = 4 \text{ minutes}
High-dose IV furosemide must be administered no faster than 20 mg/min20 \text{ mg/min} to prevent ototoxicity and hypotension.
3
Calculate the rate of administration in mL per minute.
8 mL4 minutes=2 mL/min \frac{8 \text{ mL}}{4 \text{ minutes}} = 2 \text{ mL/min}
To guide the nurse in pushing the medication safely over the required time frame.

Key Concept

Safe administration of high-alert intravenous medications requires precise calculation of both volume and administration rate to prevent iatrogenic harm, such as ototoxicity from rapid loop diuretic infusion.
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