Question

Difficulty: MediumPharmacological and Parenteral Therapies

A healthcare provider prescribes a continuous intravenous heparin infusion for a client diagnosed with a deep vein thrombosis. The client weighs 92 kg92\text{ kg}. The facility's weight-based heparin protocol requires an initial infusion rate of 18 units/kg/hr18\text{ units/kg/hr}. The pharmacy dispenses a premixed intravenous bag containing 25,000 units25,000\text{ units} of heparin in 250 mL250\text{ mL} of 5% Dextrose in Water5\%\text{ Dextrose in Water}. At what rate, in mL/hr\text{mL/hr}, should the infusion pump be programmed? Record your answer using one decimal place.

Answer: 16.6 mL/hr

Answer

16.6
The correct infusion rate is calculated by first determining the hourly weight-based dose (92 kg×18 units/kg/hr=1656 units/hr92\text{ kg} \times 18\text{ units/kg/hr} = 1656\text{ units/hr}). This dose is then divided by the concentration of the heparin solution (100 units/mL100\text{ units/mL}) to yield 16.56 mL/hr16.56\text{ mL/hr}. Rounding to one decimal place gives 16.6 mL/hr16.6\text{ mL/hr}.

Step-by-Step Solution

1
Calculate the total required hourly dose of heparin.
1656 units/hr1656\text{ units/hr}
The prescribed rate is weight-based (18 units/kg/hr18\text{ units/kg/hr}), so it must be multiplied by the client's total body weight (92 kg92\text{ kg}).
2
Determine the concentration of the intravenous heparin bag.
100 units/mL100\text{ units/mL}
To convert the hourly dose from units to milliliters, the concentration of the available solution (25,000 units÷250 mL25,000\text{ units} \div 250\text{ mL}) must be calculated.
3
Calculate the infusion pump rate.
16.56 mL/hr16.56\text{ mL/hr}
Dividing the required hourly dose (1656 units/hr1656\text{ units/hr}) by the solution concentration (100 units/mL100\text{ units/mL}) yields the volume to be infused per hour.
4
Round to the nearest tenth.
16.616.6
The question specifically asks to record the answer using one decimal place.

Key Concept

Weight-based intravenous medication dosage calculation and pump rate programming.
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