Question

Difficulty: MediumPharmacological and Parenteral Therapies

A client on a medical-surgical unit is receiving an infusion of packed red blood cells (PRBCs) for symptomatic anemia. Ten minutes after the transfusion begins, the client reports sudden severe lower back pain, dyspnea, and chills. The nurse notes visible flushing and shivering. Place the following nursing interventions in the correct order of priority. (Arrange from first action to last action.)

  1. 1Stop the blood transfusion immediately.
  2. 2Change the IV tubing and infuse 0.9% sodium chloride.
  3. 3Assess the client's vital signs and clinical status.
  4. 4Notify the primary healthcare provider and the blood bank.
  5. 5Return the blood bag, attached tubing, and labels to the blood bank.

Answer

The correct sequence of actions for a suspected blood transfusion reaction is: 1) Stop the blood transfusion immediately. 2) Change the IV tubing and infuse 0.9% sodium chloride. 3) Assess the client's vital signs and clinical status. 4) Notify the primary healthcare provider and the blood bank. 5) Return the blood bag, attached tubing, and labels to the blood bank.
In any adverse transfusion reaction, the absolute first priority is to remove the source of harm (stop the transfusion). The second priority is to maintain an open venous access line for emergency medications using entirely new tubing and normal saline. Assessing the client follows securing the line, providing the necessary clinical data to report to the healthcare provider. The provider is then notified, and finally, administrative and diagnostic protocols such as returning the blood to the lab are completed.

Step-by-Step Solution

1
Stop the transfusion immediately.
Halts the entry of incompatible blood into the client's systemic circulation.
Continuing the transfusion exacerbates the acute hemolytic reaction, increasing the risk of cardiovascular collapse and acute kidney injury.
2
Change IV tubing and run normal saline.
Maintains intravenous access without flushing the remaining blood product into the client.
If the existing tubing is used to flush normal saline, the client will receive the blood left in the line. A new line ensures safe access for emergency drugs.
3
Assess the client's vital signs and respiratory status.
Gathers objective data regarding the client's hemodynamic stability.
The nurse must have current vital signs (e.g., blood pressure, oxygen saturation) and clinical findings to accurately report the client's condition to the provider.
4
Notify the healthcare provider and blood bank.
Triggers medical intervention and laboratory investigation.
The provider will prescribe necessary emergency interventions, and the blood bank must initiate their transfusion reaction protocols.
5
Return the blood products and tubing to the blood bank.
Preserves the physical evidence of the reaction.
The blood bank must test the bag, tubing, and labels to determine if there was a crossmatching error or bacterial contamination.

Key Concept

Management of acute hemolytic transfusion reactions requires immediate cessation of the blood product, maintaining a patent IV with new tubing, and comprehensive client assessment before provider notification.
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