Question

Difficulty: MediumPharmacological and Parenteral Therapies

A nurse is caring for a client with cardiogenic shock who weighs 85 kg85 \text{ kg}. The healthcare provider prescribes a continuous intravenous (IV) infusion of dopamine at 5 mcg/kg/min5 \text{ mcg/kg/min}. The pharmacy provides an IV bag containing 400 mg400 \text{ mg} of dopamine mixed in 250 mL250 \text{ mL} of 5%5\% Dextrose in Water (D5W). At what rate should the nurse set the IV infusion pump in mL/hr\text{mL/hr}? (Record your answer to the nearest tenth.)

Answer: 15.9 mL/hr

Answer

The nurse should set the infusion pump to 15.9 mL/hr.
The correct answer is derived by calculating the weight-based dose per minute, converting it to an hourly rate, matching the units to the supplied concentration (mcg to mg), and dividing by the concentration of the dopamine bag. Finally, the value is rounded to the nearest tenth.

Step-by-Step Solution

1
Calculate the required dose per minute based on the client's weight.
85 kg×5 mcg/kg/min=425 mcg/min85 \text{ kg} \times 5 \text{ mcg/kg/min} = 425 \text{ mcg/min}
The prescription is weight-based, requiring the nurse to multiply the ordered rate by the client's weight in kg.
2
Convert the per-minute dose to a per-hour dose.
425 mcg/min×60 min/hr=25,500 mcg/hr425 \text{ mcg/min} \times 60 \text{ min/hr} = 25,500 \text{ mcg/hr}
Infusion pumps are programmed in mL per hour, so the minute dosage must be converted to an hourly rate.
3
Convert the required hourly dose from micrograms (mcg) to milligrams (mg).
25,500 mcg/hr÷1000 mcg/mg=25.5 mg/hr25,500 \text{ mcg/hr} \div 1000 \text{ mcg/mg} = 25.5 \text{ mg/hr}
The supplied medication concentration is provided in mg, so the hourly dose must match these units.
4
Calculate the concentration of the supplied IV fluid.
400 mg÷250 mL=1.6 mg/mL400 \text{ mg} \div 250 \text{ mL} = 1.6 \text{ mg/mL}
Determining the concentration simplifies the final volume calculation.
5
Calculate the final infusion rate and round to the nearest tenth.
25.5 mg/hr÷1.6 mg/mL=15.9375 mL/hr25.5 \text{ mg/hr} \div 1.6 \text{ mg/mL} = 15.9375 \text{ mL/hr}, which rounds to 15.9 mL/hr15.9 \text{ mL/hr}
Dividing the required hourly dose by the concentration yields the final pump setting.

Key Concept

Weight-based continuous IV infusion rate calculation (mcg/kg/min to mL/hr)
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