Question

Difficulty: MediumPharmacological and Parenteral Therapies

A nurse is caring for a client with cardiogenic shock who weighs 176 lbs176 \text{ lbs}. The healthcare provider prescribes a continuous intravenous (IV) infusion of dopamine at 5 mcg/kg/min5 \text{ mcg/kg/min}. The pharmacy dispenses a premixed dopamine solution of 400 mg400 \text{ mg} in 250 mL250 \text{ mL} of 5% dextrose in water5\% \text{ dextrose in water} (D5W). What rate should the nurse program the IV infusion pump to deliver the prescribed dose? Record your answer as a whole number.

Answer: 15 mL/hr

Answer

15 mL/hr
The precise infusion rate required is 15 mL/hr15 \text{ mL/hr}. This setting accurately delivers 5 mcg/kg/min5 \text{ mcg/kg/min} of dopamine to an 80 kg80 \text{ kg} client, given the supplied medication concentration of 1.6 mg/mL1.6 \text{ mg/mL} (400 mg400 \text{ mg} in 250 mL250 \text{ mL}).

Step-by-Step Solution

1
Convert the client's weight from pounds to kilograms.
176 lbs÷2.2=80 kg176 \text{ lbs} \div 2.2 = 80 \text{ kg}
The medication dosage is prescribed based on kilograms of body weight.
2
Calculate the required continuous dose of dopamine per minute.
80 kg×5 mcg/kg/min=400 mcg/min80 \text{ kg} \times 5 \text{ mcg/kg/min} = 400 \text{ mcg/min}
To determine the exact amount of medication the specific client needs every minute.
3
Convert the calculated per-minute dose to a per-hour dose.
400 mcg/min×60 min/hr=24,000 mcg/hr400 \text{ mcg/min} \times 60 \text{ min/hr} = 24,000 \text{ mcg/hr}
Standard IV infusion pumps are programmed in milliliters per hour, so the dose must be matched to an hourly timeframe.
4
Convert the hourly dose from micrograms to milligrams.
24,000 mcg/hr÷1,000 mcg/mg=24 mg/hr24,000 \text{ mcg/hr} \div 1,000 \text{ mcg/mg} = 24 \text{ mg/hr}
The dispensed IV bag concentration is provided in milligrams (400 mg400 \text{ mg}); matching units are required before the volume calculation.
5
Calculate the required fluid volume to deliver the hourly dose.
24 mg400 mg×250 mL=15 mL/hr\frac{24 \text{ mg}}{400 \text{ mg}} \times 250 \text{ mL} = 15 \text{ mL/hr}
This uses the formula: (Desired Dose / Amount on Hand) × Volume to find the final pump rate.

Key Concept

Weight-based continuous intravenous medication calculations.
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