Question

Difficulty: HardPhysiological Adaptation

A nurse is monitoring a client who is receiving a unit of packed red blood cells. Fifteen minutes into the infusion, the client reports sudden, severe lower back pain and a feeling of impending doom. The client's heart rate is 124 beats per minute, blood pressure is 86/52 mm Hg, and the nurse observes dark, reddish-brown urine in the Foley catheter tubing. Arrange the following nursing actions in the correct priority sequence from first to last.

  1. 1Stop the blood transfusion immediately.
  2. 2Disconnect the blood tubing and initiate a normal saline infusion with new tubing.
  3. 3Assess the client's cardiopulmonary status and obtain a complete set of vital signs.
  4. 4Notify the healthcare provider and the blood bank of the reaction.
  5. 5Collect required blood and urine specimens and send them with the blood bag to the laboratory.

Answer

The correct priority sequence is: 1. Stop the blood transfusion immediately. 2. Disconnect the blood tubing and initiate a normal saline infusion with new tubing. 3. Assess the client's cardiopulmonary status and obtain a complete set of vital signs. 4. Notify the healthcare provider and the blood bank of the reaction. 5. Collect required blood and urine specimens and send them with the blood bag to the laboratory.
Acute hemolytic transfusion reactions are life-threatening emergencies caused by ABO incompatibility. The absolute priority is to stop the offending agent immediately. Next, intravenous access must be maintained with new tubing and 0.9% sodium chloride to prevent hemodynamic collapse and maintain renal perfusion, while carefully avoiding flushing the incompatible blood currently in the old tubing into the client. Only after securing the line and stopping the blood should the nurse assess the client's status, notify the provider for further orders, and finally handle the diagnostic and laboratory follow-up.

Step-by-Step Solution

1
Identify the clinical presentation as an acute hemolytic transfusion reaction.
Recognize that severe lower back pain, hypotension, and dark urine are signs of hemolysis and impending shock.
Prompt recognition dictates the immediate emergency response to halt the reaction.
2
Prioritize the immediate cessation of the blood product.
The transfusion is stopped.
Removing the source of the ABO incompatibility prevents further destruction of red blood cells.
3
Establish a patent IV line with new tubing and 0.9% sodium chloride.
Intravenous access is secured for fluid resuscitation without administering the remaining incompatible blood.
Normal saline maintains vascular volume and renal perfusion, mitigating hypovolemic shock and acute kidney injury.
4
Evaluate the client's physiological status.
Cardiopulmonary assessment and vital signs are obtained.
Assessment data is necessary to determine the degree of physiological decompensation before contacting the provider.
5
Communicate findings and obtain laboratory confirmation.
The provider and blood bank are notified, and specimens are sent.
Medical interventions are prescribed based on the report, and the lab determines the exact cause of the reaction.

Key Concept

Management of Acute Hemolytic Transfusion Reaction
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