Question

Difficulty: HardPharmacological and Parenteral Therapies

A client admitted with cardiogenic shock weighs 198 lbs198\text{ lbs}. The provider initially orders a continuous intravenous (IV) infusion of dopamine at 4 mcg/kg/min4\text{ mcg/kg/min}. The pharmacy dispenses a premixed IV bag containing 800 mg800\text{ mg} of dopamine in 250 mL250\text{ mL} of 5% Dextrose5\%\text{ Dextrose} in water (D5WD_5W). Two hours later, the client's mean arterial pressure (MAP) remains at 55 mmHg55\text{ mmHg}, and the provider increases the dopamine infusion order to 7 mcg/kg/min7\text{ mcg/kg/min}. At what rate in mL/hr\text{mL/hr} should the nurse set the infusion pump to deliver the newly ordered dose? (Record your answer rounding to the nearest tenth. Do not include units in your answer.)

Answer: 11.8 mL/hr

Answer

11.8
To calculate the new IV pump rate, first convert the client's weight to kilograms (198 lbs÷2.2=90 kg198\text{ lbs} \div 2.2 = 90\text{ kg}). Next, identify the correct active dose to administer, which is the newly ordered 7 mcg/kg/min7\text{ mcg/kg/min}. Calculate the hourly dose required: 7 mcg/kg/min×90 kg=630 mcg/min7\text{ mcg/kg/min} \times 90\text{ kg} = 630\text{ mcg/min}, then multiply by 60 minutes60\text{ minutes} to determine the hourly requirement of 37,800 mcg/hr37,800\text{ mcg/hr}. Convert this value to milligrams (37.8 mg/hr37.8\text{ mg/hr}) so it matches the supplied medication's unit of measurement. Determine the IV bag concentration by dividing the total drug amount by the total volume: 800 mg÷250 mL=3.2 mg/mL800\text{ mg} \div 250\text{ mL} = 3.2\text{ mg/mL}. Finally, divide the required hourly dose by the concentration: 37.8 mg/hr÷3.2 mg/mL=11.8125 mL/hr37.8\text{ mg/hr} \div 3.2\text{ mg/mL} = 11.8125\text{ mL/hr}. According to the rounding instructions, this rounds to 11.8 mL/hr11.8\text{ mL/hr}.

Step-by-Step Solution

1
Convert the client's weight from pounds to kilograms.
198÷2.2=90 kg198 \div 2.2 = 90\text{ kg}
Weight-based medication dosing requires the weight to be in kilograms.
2
Determine the active prescribed dose.
7 mcg/kg/min7\text{ mcg/kg/min}
The provider increased the dose from the initial 4 mcg/kg/min4\text{ mcg/kg/min} due to the client's hypotensive state.
3
Calculate the required dose per minute.
7 mcg/kg/min×90 kg=630 mcg/min7\text{ mcg/kg/min} \times 90\text{ kg} = 630\text{ mcg/min}
This establishes the total micrograms of dopamine the client needs every minute.
4
Convert the minute dose to an hourly dose.
630 mcg/min×60 min/hr=37,800 mcg/hr630\text{ mcg/min} \times 60\text{ min/hr} = 37,800\text{ mcg/hr}
Intravenous infusion pumps are programmed in milliliters per hour, so the time unit must be converted.
5
Convert micrograms to milligrams.
37,800 mcg÷1,000 mcg/mg=37.8 mg/hr37,800\text{ mcg} \div 1,000\text{ mcg/mg} = 37.8\text{ mg/hr}
The medication supplied by the pharmacy is measured in milligrams, so the units must match.
6
Calculate the concentration of the supplied IV bag.
800 mg÷250 mL=3.2 mg/mL800\text{ mg} \div 250\text{ mL} = 3.2\text{ mg/mL}
This determines exactly how many milligrams of dopamine are in each milliliter of fluid.
7
Calculate the final infusion rate in mL/hr.
37.8 mg/hr÷3.2 mg/mL=11.8125 mL/hr37.8\text{ mg/hr} \div 3.2\text{ mg/mL} = 11.8125\text{ mL/hr}
Dividing the required hourly dose by the fluid concentration provides the correct pump rate.
8
Round the final answer to the nearest tenth.
11.811.8
The question explicitly specifies rounding to the nearest tenth.

Key Concept

Weight-based continuous IV infusion calculation with dose titration.
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