Question

Difficulty: EasyPharmacological and Parenteral Therapies

While caring for a client with a deep vein thrombosis, the registered nurse prepares to administer a scheduled dose of intravenous levofloxacin. The client has a single peripheral venous catheter currently infusing continuous intravenous heparin. What is the priority action the nurse must perform before proceeding?

  1. Consult a medication reference resource to confirm that levofloxacin and heparin can be safely mixed in the same line.Answer
  2. B
    Pause the continuous infusion, administer the antibiotic as a rapid bolus, and immediately resume the heparin.
  3. C
    Assign the unlicensed assistive personnel to monitor the insertion site for redness during the antibiotic administration.
  4. D
    Calculate the required drop factor to allow both fluids to infuse at the identical rate concurrently.

Answer

Consult a medication reference resource to confirm that levofloxacin and heparin can be safely mixed in the same line.
Before administering multiple intravenous medications through a single access site, the nurse must verify that the drugs are physically and chemically compatible. Failure to do so can result in crystallization, precipitation, or inactivation of the drugs, which can cause severe harm to the client, such as an embolus or loss of venous access.

Step-by-Step Solution

1
Identify that two different medications are planned to infuse through a single venous access site.
Recognized a potential risk for drug-drug incompatibility in the intravenous tubing.
Different chemical compounds can form precipitates or inactivate each other when mixed together.
2
Determine the safest intervention prior to mixing the fluids.
Selected the action of checking a drug compatibility reference.
Verifying compatibility is a required safety standard before administering any secondary intravenous medication into an active line.

Key Concept

Intravenous Medication Compatibility
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