Question

Difficulty: MediumPharmacological and Parenteral Therapies

A nurse is caring for a mechanically ventilated client who requires continuous sedation. The healthcare provider prescribes a propofol infusion at 20 mcg/kg/min20 \text{ mcg/kg/min}. The client weighs 176 lbs176 \text{ lbs}. The medication is supplied as 10 mg/mL10 \text{ mg/mL}. At what rate in mL/hr\text{mL/hr} should the nurse set the intravenous pump? (Record your answer to the nearest tenth.)

Answer: 9.6 mL/hr

Answer

9.6
To determine the correct rate, the nurse must execute a sequential calculation: convert weight to kilograms (80 kg80 \text{ kg}), find the dose per minute (1,600 mcg/min1,600 \text{ mcg/min}), convert to the dose per hour (96,000 mcg/hr96,000 \text{ mcg/hr}), translate micrograms to milligrams (96 mg/hr96 \text{ mg/hr}), and finally divide by the concentration (10 mg/mL10 \text{ mg/mL}) to arrive at the correct pump rate of 9.6 mL/hr9.6 \text{ mL/hr}.

Step-by-Step Solution

1
Convert the client's weight from pounds to kilograms.
176 lbs÷2.2 lbs/kg=80 kg176 \text{ lbs} \div 2.2 \text{ lbs/kg} = 80 \text{ kg}
The prescription is weight-based, requiring the client's mass in kilograms.
2
Calculate the total required dose per minute.
20 mcg/kg/min×80 kg=1600 mcg/min20 \text{ mcg/kg/min} \times 80 \text{ kg} = 1600 \text{ mcg/min}
Multiplying the ordered dose by the client's weight determines the specific dose needed each minute.
3
Convert the dose per minute to the dose per hour.
1600 mcg/min×60 min/hr=96,000 mcg/hr1600 \text{ mcg/min} \times 60 \text{ min/hr} = 96,000 \text{ mcg/hr}
Intravenous pumps run in hourly rates (mL/hr), so the minute-based dose must be converted to an hourly dose.
4
Convert the hourly dose from micrograms to milligrams.
96,000 mcg/hr÷1000 mcg/mg=96 mg/hr96,000 \text{ mcg/hr} \div 1000 \text{ mcg/mg} = 96 \text{ mg/hr}
The supplied medication concentration is provided in milligrams, meaning the desired dose must match this unit.
5
Calculate the final infusion rate in mL/hr.
96 mg/hr÷10 mg/mL=9.6 mL/hr96 \text{ mg/hr} \div 10 \text{ mg/mL} = 9.6 \text{ mL/hr}
Dividing the desired hourly dose by the available concentration yields the volumetric rate to program into the IV pump.

Key Concept

Weight-based Intravenous Continuous Infusion Calculations
Rate this question