Question

Difficulty: EasyPhysiological Adaptation

A client receiving a first dose of an intravenous antibiotic suddenly reports difficulty swallowing and feeling faint. The nurse observes facial swelling, audible wheezing, and a rapidly dropping blood pressure. Place the following nursing interventions in the correct sequence to manage this acute physiological emergency.

  1. 1Stop the intravenous antibiotic infusion.
  2. 2Assess airway patency and administer high-flow oxygen.
  3. 3Administer intramuscular epinephrine.
  4. 4Initiate a rapid intravenous infusion of normal saline.

Answer

The correct priority sequence is to first stop the antibiotic infusion, then assess the airway and provide oxygen, followed by administering intramuscular epinephrine, and finally initiating an intravenous normal saline infusion.
In any acute allergic or anaphylactic emergency, the clinical priority framework dictates that the nurse must first remove the offending agent to prevent further physiological deterioration. Following this, the nurse immediately applies the Airway, Breathing, Circulation (ABC) principles. The airway and breathing are stabilized through rapid assessment and supplemental oxygen. Circulation and systemic reversal of the pathophysiological response are then addressed with intramuscular epinephrine, the definitive life-saving treatment. Finally, the accompanying circulatory collapse and distributive shock are managed with rapid intravenous fluid boluses.

Step-by-Step Solution

1
Remove the causative agent
The intravenous antibiotic is immediately discontinued.
Further exposure to the allergen will worsen the anaphylactic cascade and physiological decompensation.
2
Support airway and breathing
The airway is assessed and high-flow oxygen is applied.
Anaphylaxis causes rapid airway compromise; establishing an open airway and ensuring adequate oxygenation is paramount for survival.
3
Administer primary pharmacological rescue
Intramuscular epinephrine is injected.
Epinephrine rapidly reverses the life-threatening bronchoconstriction and cardiovascular collapse associated with anaphylaxis.
4
Restore circulatory volume
An intravenous bolus of normal saline is administered.
Massive vasodilation leads to distributive shock, which requires immediate fluid resuscitation to restore adequate tissue perfusion.

Key Concept

Prioritization in Anaphylactic Shock Management
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