Question

Difficulty: MediumPharmacological and Parenteral Therapies

A nurse is preparing to administer a continuous intravenous (IV) infusion of heparin for a client diagnosed with a pulmonary embolism. The healthcare provider's prescription is for 18 units/kg/hr18 \text{ units/kg/hr}. The client's admission weight is 198 lb198 \text{ lb}. The available IV fluid is heparin 25,000 units25,000 \text{ units} in 250 mL250 \text{ mL} of 0.45%0.45\% sodium chloride.

At what rate in mL/hr\text{mL/hr} should the nurse set the IV infusion pump? (Record your answer using one decimal place.)

Answer: 16.2 mL/hr

Answer

16.2
To determine the correct IV pump rate, first convert the client's weight to kilograms (198 lb÷2.2=90 kg198 \text{ lb} \div 2.2 = 90 \text{ kg}). Next, calculate the hourly heparin dose by multiplying the weight by the prescribed rate (90 kg×18 units/kg/hr=1,620 units/hr90 \text{ kg} \times 18 \text{ units/kg/hr} = 1,620 \text{ units/hr}). Finally, divide the hourly dose by the concentration of the IV solution (25,000 units÷250 mL=100 units/mL25,000 \text{ units} \div 250 \text{ mL} = 100 \text{ units/mL}). The final rate is 1,620 units/hr÷100 units/mL=16.2 mL/hr1,620 \text{ units/hr} \div 100 \text{ units/mL} = 16.2 \text{ mL/hr}.

Step-by-Step Solution

1
Convert the client's weight from pounds (lb) to kilograms (kg).
198 lb÷2.2=90 kg198 \text{ lb} \div 2.2 = 90 \text{ kg}
The medication is prescribed based on the client's weight in kilograms, so a conversion is necessary before calculating the dose.
2
Calculate the hourly dose of heparin required in units.
90 kg×18 units/kg/hr=1,620 units/hr90 \text{ kg} \times 18 \text{ units/kg/hr} = 1,620 \text{ units/hr}
Multiplying the weight by the weight-based prescription provides the total amount of medication needed per hour.
3
Determine the concentration of the supplied IV heparin solution.
25,000 units÷250 mL=100 units/mL25,000 \text{ units} \div 250 \text{ mL} = 100 \text{ units/mL}
Finding the concentration per milliliter is required to convert the hourly dose from units into a volume (mL).
4
Calculate the infusion pump rate in mL/hr.
1,620 units/hr÷100 units/mL=16.2 mL/hr1,620 \text{ units/hr} \div 100 \text{ units/mL} = 16.2 \text{ mL/hr}
Dividing the required hourly dose by the concentration provides the volume to be infused over one hour.

Key Concept

Weight-based intravenous continuous infusion calculation
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