Question

Difficulty: MediumPharmacological and Parenteral Therapies

A nurse is caring for a pediatric client who weighs 22 kg22\text{ kg}. The healthcare provider has prescribed intravenous ceftriaxone 50 mg/kg/day50\text{ mg/kg/day} divided into two equal doses. The pharmacy dispenses a ceftriaxone vial reconstituted to a concentration of 1 g1\text{ g} per 10 mL10\text{ mL}. How many milliliters (mL\text{mL}) should the nurse administer for a single dose? Record your answer to one decimal place.

Answer: 5.5 mL

Answer

5.5
The correct answer is 5.5 mL5.5\text{ mL}. First, determine the daily dose: 22 kg×50 mg/kg=1100 mg/day22\text{ kg} \times 50\text{ mg/kg} = 1100\text{ mg/day}. Next, divide this by 2 for the single dose: 1100 mg÷2=550 mg1100\text{ mg} \div 2 = 550\text{ mg}. The concentration is 1 g(1000 mg)1\text{ g} (1000\text{ mg}) in 10 mL10\text{ mL}, which equals 100 mg/mL100\text{ mg/mL}. Finally, 550 mg÷100 mg/mL=5.5 mL550\text{ mg} \div 100\text{ mg/mL} = 5.5\text{ mL}.

Step-by-Step Solution

1
Calculate the total daily dose based on the client's weight.
1100 mg/day1100\text{ mg/day}
The prescription is given as a weight-based daily total (50 mg/kg/day50\text{ mg/kg/day}).
2
Divide the total daily dose into the single administration dose.
550 mg/dose550\text{ mg/dose}
The medication is to be divided into two equal doses per day.
3
Convert the supplied medication concentration into milligrams.
1000 mg1000\text{ mg} per 10 mL10\text{ mL}, or 100 mg/mL100\text{ mg/mL}
The vial is labeled in grams (1 g1\text{ g}), but the calculated dose is in milligrams.
4
Calculate the final liquid volume to administer.
5.5 mL5.5\text{ mL}
To find the exact volume of the reconstituted liquid that contains the 550 mg550\text{ mg} single dose.

Key Concept

Weight-based pediatric medication dosage and liquid concentration calculation.
Estimated Time:2m 0s
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