Question

Difficulty: HardReduction of Risk Potential

A nurse is preparing to obtain a blood specimen for a comprehensive metabolic panel from a client's multi-lumen central venous catheter (CVC). A continuous infusion of parenteral nutrition is currently running through an adjacent lumen. To reduce the risk of pre-analytical laboratory errors and maintain line patency, in what order should the nurse perform the following actions? (Arrange the items in the correct chronological sequence.)

  1. 1Stop the continuous parenteral nutrition infusion.
  2. 2Cleanse the needleless connector and flush the lumen with 0.9% sodium chloride.
  3. 3Aspirate and discard the initial 5 mL of blood.
  4. 4Obtain the required volume of blood for the laboratory specimen.
  5. 5Flush the catheter with 0.9% sodium chloride and restart the infusion.

Answer

The correct sequence requires the nurse to first halt the continuous infusion, verify patency with a saline flush, clear the dead space of residual fluid by discarding an initial blood volume, collect the pure diagnostic sample, and finally flush the line again before resuming the parenteral nutrition.
Drawing blood from a multi-lumen central venous catheter carries a high risk of pre-analytical laboratory error if the sample is contaminated by concurrent infusions or diluted by flush solutions. Adhering to the standard sequence—pausing adjacent infusions, scrubbing the hub and flushing to confirm patency, utilizing a discard volume to clear dead space, drawing the diagnostic sample, and providing a final flush—ensures highly accurate laboratory data and preserves long-term catheter function.

Step-by-Step Solution

1
Pause the continuous parenteral nutrition infusion.
Halts the delivery of intravenous fluids and nutrients.
Prevents the parenteral nutrition from artificially elevating glucose and electrolyte levels in the drawn blood sample.
2
Cleanse the needleless connector and flush with 0.9% sodium chloride.
Decontaminates the access point and verifies lumen patency.
Prevents intraluminal microbial contamination and ensures the catheter is viable for blood return without damaging the vessel.
3
Aspirate and discard the initial 5 mL of blood.
Removes the saline flush and stagnant fluid from the catheter.
Prevents hemodilution, ensuring the diagnostic sample accurately reflects the client's systemic venous blood composition.
4
Collect the required blood volume.
Secures the diagnostic specimen.
Fulfills the prescribed diagnostic test using an undiluted, uncontaminated blood source.
5
Flush the catheter with 0.9% sodium chloride and restart the infusion.
Clears residual blood from the line and resumes therapy.
Prevents fibrin formation and subsequent catheter occlusion while maintaining the client's vital nutritional support.

Key Concept

Strict sequential protocols for central venous catheter blood sampling—including pausing infusions and discarding initial waste volumes—are essential to mitigate the risk of pre-analytical laboratory errors and inappropriate clinical interventions.
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