Question

Difficulty: HardPharmacological and Parenteral Therapies

A client in cardiogenic shock is receiving a continuous intravenous (IV) infusion of dopamine through a single-lumen peripheral IV line. The healthcare provider prescribes a stat dose of furosemide 120120 mg IV push for acute pulmonary edema. The facility protocol dictates that furosemide should not be administered faster than 2020 mg/minute to prevent adverse effects. Furosemide is physically incompatible with dopamine. Based on these parameters, which action by the nurse is the safest and most appropriate?

  1. Establish a second peripheral IV access and administer the furosemide over a minimum of 66 minutes.Answer
  2. B
    Pause the dopamine infusion, flush the IV line with normal saline, administer the furosemide over 66 minutes, and resume the dopamine.
  3. C
    Administer the furosemide through the lowest Y-site port on the primary IV tubing over a minimum of 66 minutes.
  4. D
    Establish a second peripheral IV access and administer the furosemide over 22 minutes to ensure rapid relief of the pulmonary edema.

Answer

The safest and most appropriate action is to establish a second peripheral IV access and administer the furosemide over a minimum of 66 minutes.
This action correctly addresses all three critical safety factors in the scenario. First, calculating 120120 mg at a maximum rate of 2020 mg/minute dictates a minimum administration time of 66 minutes to prevent ototoxicity. Second, because furosemide and dopamine are physically incompatible, they cannot be mixed in the same line. Third, dopamine is a life-sustaining vasoactive infusion with a half-life of roughly 22 minutes; pausing it for 66 or more minutes would result in a severe, potentially fatal drop in blood pressure. Therefore, establishing a separate, dedicated IV line is the only action that safely accommodates the continuous vasopressor and the slow IV push of an incompatible medication.

Step-by-Step Solution

1
Analyze the prescribed dose and maximum administration rate.
Dividing 120120 mg by the maximum rate of 2020 mg/minute yields a minimum administration time of 66 minutes.
Calculating the correct IV push time is critical to prevent adverse effects like ototoxicity.
2
Evaluate the physical compatibility of the medications.
Furosemide and dopamine are incompatible and cannot be mixed in the same IV line.
Mixing them at the Y-site would cause an immediate chemical reaction and precipitate formation.
3
Determine the physiological impact of pausing the continuous infusion.
Dopamine is a critical vasoactive medication with a very short half-life. It cannot be safely paused for 66 minutes.
Interrupting the vasopressor would likely cause catastrophic hemodynamic collapse in a client with cardiogenic shock.
4
Synthesize the findings to select the safest administration method.
Establishing a second, dedicated peripheral IV access is required.
This allows the safe, slow administration of furosemide without interrupting the life-sustaining dopamine infusion.

Key Concept

Safe Parenteral Administration of Incompatible High-Risk Medications
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