Question

Difficulty: MediumPharmacological and Parenteral Therapies

A nurse is caring for a client with acute decompensated heart failure who is prescribed a continuous intravenous infusion of dobutamine at 5 mcg/kg/min5\text{ mcg/kg/min}. The client weighs 187 lbs187\text{ lbs}. The pharmacy provides dobutamine as 500 mg500\text{ mg} mixed in 250 mL250\text{ mL} of 5% dextrose in water5\%\text{ dextrose in water} (D5W). How many mL/hr\text{mL/hr} should the nurse set the infusion pump to deliver? (Record your answer to the nearest tenth.)

Answer: 12.8 mL/hr

Answer

12.8
To determine the correct infusion pump setting in mL/hr\text{mL/hr}, the nurse must perform a multi-step calculation involving unit conversions for both weight (pounds to kilograms) and time (minutes to hours). After establishing that the client needs 25.5 mg25.5\text{ mg} of dobutamine every hour, dividing by the concentration of the IV bag (2 mg/mL2\text{ mg/mL}) provides the accurate volume of 12.75 mL/hr12.75\text{ mL/hr}, which rounds to 12.8 mL/hr12.8\text{ mL/hr}.

Step-by-Step Solution

1
Convert the client's weight from pounds to kilograms.
187÷2.2=85 kg187 \div 2.2 = 85\text{ kg}
The medication dosage is prescribed based on kilograms of body weight.
2
Calculate the per-minute dobutamine dose for this specific client.
85 kg×5 mcg/kg/min=425 mcg/min85\text{ kg} \times 5\text{ mcg/kg/min} = 425\text{ mcg/min}
This establishes the exact amount of medication the client needs to receive every minute.
3
Convert the minute dose to an hourly dose.
425 mcg/min×60 min/hr=25,500 mcg/hr425\text{ mcg/min} \times 60\text{ min/hr} = 25,500\text{ mcg/hr}
Intravenous infusion pumps are programmed in milliliters per hour, so the dose must reflect an hourly rate.
4
Convert the hourly dose from micrograms to milligrams.
25,500 mcg/hr÷1000 mcg/mg=25.5 mg/hr25,500\text{ mcg/hr} \div 1000\text{ mcg/mg} = 25.5\text{ mg/hr}
The supplied medication from the pharmacy is measured in milligrams, so the units must match.
5
Calculate the concentration of the provided IV bag.
500 mg÷250 mL=2 mg/mL500\text{ mg} \div 250\text{ mL} = 2\text{ mg/mL}
This determines how many milligrams of dobutamine are in each milliliter of the IV fluid.
6
Determine the final infusion rate in mL/hr.
25.5 mg/hr÷2 mg/mL=12.75 mL/hr25.5\text{ mg/hr} \div 2\text{ mg/mL} = 12.75\text{ mL/hr}
Dividing the required hourly medication dose by the medication concentration yields the fluid volume needed per hour.
7
Round the final value to the nearest tenth as instructed.
12.8 mL/hr12.8\text{ mL/hr}
Standard rounding rules dictate that a 5 in the hundredths place rounds the tenths place up.

Key Concept

Weight-based continuous intravenous infusion dosage calculation requiring conversion between units of mass and time.
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