Question

Difficulty: HardPharmacological and Parenteral Therapies

A registered nurse is caring for a client who is receiving an intravenous infusion of packed red blood cells (PRBCs). Fifteen minutes into the transfusion, the client reports sudden lower back pain, chills, and shortness of breath. Arrange the following nursing actions in the correct priority order.

  1. 1Stop the blood transfusion immediately.
  2. 2Disconnect the blood tubing and connect a new intravenous tubing primed with normal saline.
  3. 3Assess the client's vital signs and respiratory status.
  4. 4Notify the healthcare provider and the blood bank of the suspected reaction.
  5. 5Send the remaining blood product, attached tubing, and labels back to the blood bank.

Answer

Stop the blood transfusion, disconnect the blood tubing and connect new tubing with normal saline, assess vital signs, notify the healthcare provider and blood bank, and finally send the blood bag and tubing to the blood bank.
When a client experiences an acute hemolytic transfusion reaction, the nurse's first action is always to stop the transfusion. Next, the nurse must maintain a patent IV line with normal saline using completely new tubing to avoid pushing residual blood into the client. Only after the client is secured from further harm and the line is patent should the nurse assess the client's vital signs. This assessment data is then communicated to the healthcare provider and blood bank. Finally, as part of the post-reaction protocol, the remaining blood, tubing, and labels are sent to the blood bank for analysis.

Step-by-Step Solution

1
Recognize the signs of a transfusion reaction and immediately stop the infusion.
Further administration of the incompatible blood product is halted.
Lower back pain, chills, and shortness of breath indicate a potentially fatal acute hemolytic reaction. Stopping the source is the top priority.
2
Maintain IV access using a new tubing setup primed with normal saline.
A patent IV line is established for emergency drug administration.
Using the existing blood tubing to flush the line would push the remaining hemolyzed blood into the client's circulation, worsening the reaction.
3
Assess the client to gather baseline data.
The nurse obtains current vital signs, oxygen saturation, and lung sounds.
The healthcare provider will need this critical assessment data to prescribe appropriate emergency interventions.
4
Notify the healthcare provider and the blood bank.
The medical team is activated and the blood bank initiates their reaction protocol.
The provider must order specific treatments, and the blood bank must be alerted to a potential crossmatch error.
5
Return the blood product and equipment to the blood bank.
The blood bank receives the materials necessary for investigation.
Analyzing the remaining blood and tubing helps identify the specific cause of the reaction and prevents further errors.

Key Concept

Management of acute hemolytic transfusion reactions requires immediately stopping the transfusion and maintaining line patency with new tubing before assessing and reporting.
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