A 28-year-old primiparous woman experiences significant vaginal bleeding immediately following the vaginal delivery of a 4100-g neonate. The delivery was complicated by a prolonged second stage, and aggressive umbilical cord traction was applied before complete placental separation. On physical examination, a firm, beefy-red mass is visualized protruding through the vaginal introitus, and the uterine fundus is no longer palpable transabdominally. The patient's blood pressure is 78/40 mmHg and her heart rate is 132/min. Intravenous fluid resuscitation and massive transfusion protocols are initiated.
Assuming each conservative measure fails to achieve resolution, arrange the following interventions in the correct chronological sequence for the optimal management of this patient's condition.
- 1Discontinue all active uterotonic infusions
- 2Attempt immediate manual replacement of the uterus
- 3Administer a uterine relaxant such as intravenous nitroglycerin
- 4Perform laparotomy for surgical correction
- 5Administer uterotonic agents such as oxytocin and methylergonovine