Match each classic pediatric infectious disease clinical presentation with its correct causative pathogen.
- A 5-year-old child presents with bright red cheeks, appearing as though they were slapped, followed by a lacy, reticular rash on the torso and extremities.Parvovirus B19
- A 9-month-old infant develops a high fever for 3 days; abruptly after the fever breaks, a rosy pink maculopapular rash appears on the trunk.Human herpesvirus 6 (HHV-6)
- A 3-year-old child develops painful oral ulcers along with a vesicular rash on the palms of the hands and soles of the feet.Coxsackievirus A
- A 6-year-old child presents with fever, exudative pharyngitis, and a finely papular, 'sandpaper-like' rash with circumoral pallor.Streptococcus pyogenes
Answer
The presentations map respectively to: Parvovirus B19, Human herpesvirus 6 (HHV-6), Coxsackievirus A, and Streptococcus pyogenes.
Each pediatric exanthem has a highly characteristic clinical presentation that allows for clinical diagnosis without the need for extensive laboratory testing. Parvovirus B19 causes the 'slapped cheek' rash (Erythema infectiosum); HHV-6 causes a rash that appears only after the fever breaks (Roseola); Coxsackievirus A causes vesicular lesions on the hands, feet, and oral mucosa (Hand-foot-and-mouth disease); and Streptococcus pyogenes causes a distinct sandpaper-like rash with pharyngitis (Scarlet fever).
Step-by-Step Solution
Key Concept
Classic presentations of pediatric exanthems and their causative viral or bacterial pathogens.
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