Question

Difficulty: MediumStatistical Inference and Hypothesis Testing

A team of clinical researchers is investigating the efficacy of a new intensive lifestyle modification program on glycemic control in patients with newly diagnosed type 2 diabetes. In a study of 144144 patients, the mean reduction in hemoglobin A1c (HbA1c) after six months is 1.2%1.2\%. The sample standard deviation for this reduction is 0.6%0.6\%. Assuming a normal distribution of the data and using a critical z-score of 1.961.96 for the 95%95\% confidence level, what is the upper bound of the 95%95\% confidence interval for the mean reduction in HbA1c in this population? (Express your answer to three decimal places.)

Answer: 1.298 %

Answer

1.298
The 95%95\% confidence interval provides a range of values within which the true population mean is expected to fall. It is calculated using the sample mean, the standard error of the mean, and the corresponding z-score. The standard error (SE) is determined by dividing the standard deviation by the square root of the sample size (SE=0.6/144=0.05SE = 0.6 / \sqrt{144} = 0.05). The margin of error is the product of the z-score and the SE (1.96×0.05=0.0981.96 \times 0.05 = 0.098). The upper bound is calculated by adding this margin to the sample mean (1.2+0.098=1.2981.2 + 0.098 = 1.298).

Step-by-Step Solution

1
Calculate the standard error (SE) of the mean.
0.6/144=0.050.6 / \sqrt{144} = 0.05
SE quantifies the precision of the sample mean estimate and is necessary for constructing the confidence interval.
2
Calculate the margin of error.
1.96×0.05=0.0981.96 \times 0.05 = 0.098
The margin of error defines the width of the confidence interval on either side of the mean.
3
Calculate the upper bound of the 95% confidence interval.
1.2+0.098=1.2981.2 + 0.098 = 1.298
The upper bound is found by adding the margin of error to the point estimate (mean).

Key Concept

The confidence interval for a sample mean is calculated as Mean±(z−score×StandardError)Mean \pm (z-score \times Standard Error), where Standard Error is the standard deviation divided by the square root of the sample size.
Rate this question