Match each patient's clinical presentation of an adverse drug reaction to the psychotropic medication most likely responsible for their symptoms.
- A patient develops a severe inner sense of restlessness and an uncontrollable urge to pace two weeks after initiating treatment for schizophrenia.Haloperidol
- A patient treated for bipolar disorder presents with increased thirst, frequent urination, and a fine bilateral hand tremor.Lithium
- A patient treated for major depressive disorder and insomnia presents to the emergency department with a painful, prolonged erection lasting over four hours.Trazodone
- A patient receiving treatment for refractory psychotic symptoms presents with a fever, severe pharyngitis, and an absolute neutrophil count of 300/mm³.Clozapine
- A patient recently started on a mood stabilizer for bipolar depression develops a rapidly spreading, painful blistering rash with oral mucosal ulcerations.Lamotrigine
Answer
The correct matches are: Restlessness (akathisia) with Haloperidol; Polyuria and tremor with Lithium; Priapism with Trazodone; Agranulocytosis with Clozapine; and Blistering rash with Lamotrigine.
Each psychotropic medication has a distinct and highly tested adverse effect profile. Recognizing these specific toxicities is crucial for appropriate monitoring and safe psychopharmacologic management.
Step-by-Step Solution
Key Concept
Adverse effect profiles of psychotropic medications