A 68-year-old man presents to the clinic for evaluation of progressive shortness of breath, fatigue, and right-sided abdominal discomfort that has worsened over the past three weeks. One month ago, he underwent uncomplicated placement of a dual-chamber transvenous pacemaker for symptomatic third-degree atrioventricular block. His medical history includes severe chronic obstructive pulmonary disease, for which he uses a daily inhaled long-acting muscarinic antagonist and an inhaled corticosteroid-long-acting beta-agonist combination.
Vital signs show a temperature of (), blood pressure of , and a paced pulse of . Oxygen saturation is on room air.
Physical examination reveals distended neck veins while sitting at a angle, with a jugular venous pressure of and a prominent, rapid positive wave occurring during ventricular systole. Pulmonary auscultation demonstrates a prolonged expiratory phase with scattered bilateral wheezes. Cardiac examination reveals a regular rate and a grade blowing holosystolic murmur at the left lower sternal border that becomes louder during inspiration. The liver is enlarged and exhibits a palpable systolic pulsation. There is pitting edema in both lower extremities up to the knees. Laboratory studies show a normal leukocyte count and a serum creatinine of .
Which of the following is the most appropriate next step in the management of this patient?
- Transthoracic echocardiographyAnswer
- BInitiation of systemic glucocorticoids and nebulized albuterol
- CIntravenous administration of broad-spectrum antibiotics and blood cultures
- DInterrogation of the pacemaker to shorten the atrioventricular delay
- EContrast-enhanced computed tomography of the chest