Question

Difficulty: EasyCardiovascular System

A 58-year-old man presents to the emergency department with acute-onset, crushing substernal chest pain radiating to his left jaw that began 45 minutes ago. He is diaphoretic and appears distressed. Vital signs show a blood pressure of 145/90 mm Hg and a heart rate of 92/min. Arrange the following steps in the most appropriate chronological order for the initial diagnosis and definitive management of this patient's condition.

  1. 1Perform and interpret a rapid 12-lead electrocardiogram (ECG)
  2. 2Administer chewable aspirin and a P2Y12 receptor inhibitor
  3. 3Transfer the patient urgently to the cardiac catheterization laboratory
  4. 4Perform primary percutaneous coronary intervention (PCI)

Answer

The correct sequence is: 1) Perform a 12-lead ECG, 2) administer dual antiplatelet therapy, 3) transfer to the catheterization lab, and 4) perform primary PCI.
In a patient presenting with classic symptoms of acute coronary syndrome, the immediate priority is to perform a 12-lead ECG to differentiate between a STEMI and other causes of chest pain. Once a STEMI is diagnosed, early pharmacological intervention with chewable aspirin and a P2Y12 inhibitor is indicated. Following this, the patient should be rapidly transferred to the cardiac catheterization laboratory where primary percutaneous coronary intervention (PCI) is performed to definitively restore coronary perfusion.

Step-by-Step Solution

1
Perform a 12-lead ECG
Identifies ST-segment elevations or other ischemic changes
To rapidly diagnose the cause of acute chest pain, specifically to rule in or rule out a STEMI within 10 minutes of arrival.
2
Administer dual antiplatelet therapy
Inhibits platelet aggregation
To prevent further expansion of the intracoronary thrombus once an acute coronary syndrome is confirmed.
3
Transfer to the cardiac catheterization laboratory
Prepares the patient for definitive interventional therapy
To facilitate urgent mechanical revascularization, aiming for a door-to-balloon time of less than 90 minutes.
4
Perform primary PCI
Restores antegrade coronary blood flow
Definitively treats the underlying pathophysiology of a STEMI by opening the occluded vessel.

Key Concept

The timely diagnosis and sequential management of ST-elevation myocardial infarction (STEMI).
Rate this question