Question

Difficulty: EasyOrdering Imaging Studies

A 42-year-old female presents to the emergency department with a 6-hour history of severe right upper quadrant abdominal pain that radiates to her right scapula. The pain started 30 minutes after eating a large, fatty meal. She also reports nausea and two episodes of vomiting. Her temperature is 38.2°C (100.8°F), blood pressure is 130/80 mmHg, pulse is 98/min, and respirations are 16/min. Physical examination reveals focal tenderness to palpation in the right upper quadrant with sudden inspiratory arrest upon deep palpation. Laboratory studies show a leukocyte count of 14,000/mm³ and normal liver function tests. Which of the following is the most appropriate next step in imaging for this patient?

  1. A
    Computed tomography (CT) scan of the abdomen and pelvis with intravenous contrast
  2. B
    Hepatobiliary iminodiacetic acid (HIDA) scan
  3. C
    Magnetic resonance cholangiopancreatography (MRCP)
  4. Right upper quadrant abdominal ultrasoundAnswer
  5. E
    Upright plain abdominal radiograph

Answer

Right upper quadrant abdominal ultrasound
The patient's clinical presentation of postprandial right upper quadrant pain, fever, leukocytosis, and a positive Murphy sign is classic for acute cholecystitis. The most appropriate initial imaging study for suspected acute cholecystitis is a right upper quadrant abdominal ultrasound. It is highly sensitive for detecting gallstones, gallbladder wall thickening (>3 mm), and pericholecystic fluid, while remaining cost-effective and avoiding ionizing radiation.

Step-by-Step Solution

1
Analyze the patient's clinical presentation and physical examination findings.
The patient has postprandial right upper quadrant pain radiating to the scapula, fever, leukocytosis, and a positive Murphy sign (inspiratory arrest on palpation).
Identifying the classic triad of right upper quadrant pain, fever, and leukocytosis establishes a high clinical suspicion for acute cholecystitis.
2
Determine the most appropriate initial diagnostic imaging modality based on clinical guidelines.
Right upper quadrant abdominal ultrasound is identified as the first-line test.
Ultrasound is non-invasive, lacks ionizing radiation, and is highly sensitive and specific for visualizing gallstones, gallbladder wall thickening, and pericholecystic fluid.

Key Concept

Right upper quadrant abdominal ultrasound is the preferred and most cost-effective initial imaging modality for patients presenting with signs and symptoms of acute cholecystitis.
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