A 55-year-old male patient is admitted to the intensive care unit with septic shock secondary to a perforated appendix. The medical team decides to insert a central venous catheter for the administration of targeted vasopressor therapy and hemodynamic monitoring. The resident physician prepares to perform the procedure at the right subclavian vein site. To minimize the risk of a central line-associated bloodstream infection (CLABSI), the resident adheres to the hospital's standardized infection control bundle. The resident performs surgical hand antisepsis and dons a surgical cap, a mask covering the nose and mouth, a sterile gown, and sterile gloves. The skin at the insertion site is thoroughly prepped with a 2% chlorhexidine and 70% isopropyl alcohol solution and allowed to dry completely. Which of the following is the most appropriate additional intervention required to minimize the risk of a central line-associated bloodstream infection in this patient?
- Cover the patient entirely with a large sterile drape during the procedureAnswer
- BAdminister a prophylactic dose of intravenous vancomycin prior to insertion
- CApply a topical antibiotic ointment to the insertion site after securing the line
- DReplace the central venous catheter routinely over a guidewire every 72 hours
- EObtain daily screening blood cultures from the catheter port