Question

Difficulty: MediumPreventive Care and Screening

Match each of the following ambulatory patient profiles with the single most appropriate guideline-concordant preventive care intervention. Each patient is asymptomatic, has no acute complaints, and has a normal physical examination today.

  • A 41-year-old woman, BMI 23 kg/m², never-smoker. Her last cervical cancer screening with primary HPV testing was at age 38 and was negative.Biennial screening mammography
  • A 58-year-old man, BMI 26 kg/m², who currently smokes 1 pack of cigarettes daily and has done so for the last 25 years. He had a normal screening colonoscopy at age 52.Annual low-dose computed tomography (LDCT) of the chest
  • A 23-year-old woman, BMI 24 kg/m², non-smoker. She is sexually active with a new male partner. Her last cervical cytology was normal at age 21.Nucleic acid amplification testing for Chlamydia trachomatis and Neisseria gonorrhoeae
  • A 66-year-old man, BMI 25 kg/m². He smoked a half-pack of cigarettes daily for 10 years but quit at age 30. He had a normal screening colonoscopy at age 64.One-time screening duplex ultrasonography of the abdomen

Answer

The 41-year-old woman requires screening mammography; the 58-year-old man requires LDCT of the chest; the 23-year-old woman requires chlamydia and gonorrhea screening; and the 66-year-old man requires an abdominal ultrasound for AAA screening.
Each patient requires a specific preventive intervention based on current USPSTF guidelines. The 41-year-old woman needs a mammogram (recommended starting at age 40). The 58-year-old smoker meets all criteria for LDCT (age 50-80, 20+ pack-years). The 23-year-old woman needs STI screening (sexually active, age <25). The 66-year-old former smoker needs an abdominal ultrasound for AAA (men 65-75, any smoking history >100 cigarettes).

Step-by-Step Solution

1
Analyze the 41-year-old woman's profile.
Identified as due for screening mammography.
Current USPSTF guidelines recommend initiating biennial screening mammography at age 40. Her cervical cancer screening (primary HPV at age 38) is valid for 5 years.
2
Analyze the 58-year-old man's profile.
Identified as due for annual low-dose computed tomography (LDCT) of the chest.
He falls within the 50-80 age range, has a >20 pack-year smoking history, and is a current smoker, meeting all criteria for lung cancer screening. Colorectal screening is not due until age 62.
3
Analyze the 23-year-old woman's profile.
Identified as due for chlamydia and gonorrhea screening.
She is a sexually active woman younger than 25, which is a Grade B indication for STI screening. Her Pap smear (done at 21) is valid for 3 years, so she is not due for cervical cancer screening until age 24.
4
Analyze the 66-year-old man's profile.
Identified as due for a one-time abdominal duplex ultrasound.
He is a man between 65 and 75 years old who has a lifetime smoking history of at least 100 cigarettes (5 pack-years), meeting the criteria for abdominal aortic aneurysm screening.

Key Concept

Application of USPSTF preventive care guidelines tailored to age, biological sex, and specific clinical risk factors.
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