Question

A 24-year-old woman is brought to the emergency department by ambulance due to severe shortness of breath, wheezing, and a tight chest that began 2 hours ago. She has a history of moderate persistent asthma but has not used her inhalers for the past week. On arrival, she appears anxious and is using accessory muscles of respiration. Her temperature is $37.1^\circ\text{C}$ ($98.8^\circ\text{F}$), blood pressure is $135/85\text{ mm Hg}$, pulse is $118/\text{min}$, and respiratory rate is $28/\text{min}$. Oxygen saturation is $92\%$ on room air. Physical examination reveals diffuse bilateral end-expiratory and inspiratory wheezes. Laboratory studies show a leukocyte count of $12,500/\text{mm}^3$ with a normal differential. Which of the following pharmacologic interventions should be administered as part of her immediate initial management? (Select all that apply)