A 28-year-old woman arrives at the emergency department due to severe, progressive right lower quadrant abdominal pain over the past 12 hours, accompanied by nausea and vomiting. Vital signs show a temperature of 38.3°C (100.9°F), blood pressure of 112/72 mmHg, and pulse of 105/min. Physical examination demonstrates localized rigidity and rebound tenderness in the right lower quadrant. A complete blood count reveals a leukocyte count of 16,000/mm³. Cross-sectional imaging of the abdomen and pelvis confirms acute, uncomplicated appendicitis. The surgical team schedules an urgent laparoscopic appendectomy. Which of the following interventions are appropriate in the immediate preoperative management of this patient? (Select all that apply)
- Administration of isotonic intravenous fluidsAnswer
- Administration of broad-spectrum intravenous antibioticsAnswer
- CDelaying the operation to obtain magnetic resonance imaging of the abdomen
- DAdministration of therapeutic-dose subcutaneous enoxaparin
- EDischarge to home with oral antibiotics and a scheduled outpatient follow-up in 48 hours
Answer
The appropriate interventions are the administration of isotonic intravenous fluids and the administration of broad-spectrum intravenous antibiotics.
The correct interventions are the administration of isotonic intravenous fluids and broad-spectrum intravenous antibiotics. In a patient presenting with acute appendicitis and clinical signs of volume depletion (vomiting, tachycardia, fever), immediate preoperative management must prioritize hemodynamic stabilization with intravenous fluids. Additionally, broad-spectrum antibiotics covering gastrointestinal flora (gram-negative rods and anaerobes) are the standard of care to prevent surgical site infections and control the underlying infection before the primary incision.
Step-by-Step Solution
Key Concept
Essential preoperative management for urgent abdominal surgery (e.g., acute appendicitis) includes prompt fluid resuscitation and administration of prophylactic broad-spectrum intravenous antibiotics.
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