Question

Difficulty: MediumMeasures of Disease Frequency

A public health physician is reviewing annual surveillance statistics for a municipality with a total population of 250,000250,000 individuals. Over the course of the previous year, there were 2,0002,000 recorded deaths from all causes. The health department's registry indicates that 5,0005,000 residents were living with chronic liver disease during this same period. Death certificate analysis reveals that 400400 of the total deaths were directly attributed to complications of chronic liver disease. The physician is tasked with preparing a brief regarding the relative burden of different causes of death. Based on this data, what is the proportionate mortality for chronic liver disease in this municipality?

  1. A
    0.16%0.16\%
  2. B
    0.8%0.8\%
  3. C
    2.0%2.0\%
  4. D
    8.0%8.0\%
  5. 20.0%20.0\%Answer

Answer

20.0%20.0\%
Proportionate mortality measures the percentage of all deaths in a given population that are attributed to a specific cause. It is calculated by dividing the number of deaths from the specific cause by the total number of deaths from all causes, and then multiplying by 100100. In this scenario, there were 400400 deaths from chronic liver disease and 2,0002,000 total deaths from all causes. The calculation is (4002,000)×100=20.0%(\frac{400}{2,000}) \times 100 = 20.0\%. This epidemiological metric is highly useful for health departments to identify the leading causes of death and prioritize public health resources, although it does not measure the risk of dying from the disease for a healthy member of the general population.

Step-by-Step Solution

1
Identify the numerator for the calculation.
The numerator is the number of deaths attributed to the specific cause (chronic liver disease), which is 400400.
Proportionate mortality specifically looks at the subset of total deaths caused by the disease of interest.
2
Identify the appropriate denominator for the calculation.
The denominator is the total number of deaths from all causes in the population, which is 2,0002,000.
Unlike cause-specific mortality (which uses the total population) or case fatality rate (which uses the number of people with the disease), proportionate mortality compares disease-specific deaths to overall deaths.
3
Calculate the percentage.
4002,000×100=20.0%\frac{400}{2,000} \times 100 = 20.0\%
This yields the proportion of all deaths that were caused by chronic liver disease.

Key Concept

Proportionate mortality is the proportion of total deaths in a population that are attributed to a specific cause, calculated as (deaths from specific cause / total deaths) × 100.
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