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Zorluk: OrtaEvolution and Adaptation

A hospital laboratory discovers that a strain of pathogenic bacteria has developed widespread resistance to a standard antibiotic over several years of clinical use. According to the principles of natural selection, how did this antibiotic resistance most likely arise within the bacterial population?

  1. A
    Individual bacteria sensed the chemical stress and actively modified their cell structures during their lifetime to survive the antibiotic.
  2. Bacteria with pre-existing genetic variations for resistance survived antibiotic exposure and reproduced, passing the trait to subsequent generations.Cevap
  3. C
    The resistance trait spread rapidly through the population solely because dominant alleles automatically increase in frequency regardless of environmental selection.
  4. D
    Non-resistant bacterial cells absorbed viral antibodies from patient bloodstreams to intentionally neutralize the antibiotic medication.

Cevap

Bacteria with pre-existing genetic variations for resistance survived antibiotic exposure and reproduced, passing the trait to subsequent generations.
Natural selection operates on populations through differential survival and reproduction. Within the bacterial population, random genetic mutations provide pre-existing variation. When the antibiotic is introduced, it creates a selective pressure that eliminates susceptible bacteria while allowing resistant individuals to survive and reproduce. Over successive generations, the frequency of resistance alleles increases across the population.

Adım Adım Çözüm

1
Identify the source of variation in the population
Random genetic mutations create natural variation among individual bacteria prior to antibiotic exposure.
Natural selection requires inherited variation to already exist within a population.
2
Apply environmental selection pressure
Susceptible bacteria are killed by the antibiotic, while individuals carrying resistance mutations survive.
The antibiotic acts as a selective agent favoring resistant phenotypes.
3
Evaluate the reproductive outcome over generations
Surviving resistant bacteria reproduce, increasing the proportion of resistant individuals in subsequent generations.
Evolution is a population-level change in allele frequency over time.

Anahtar Kavram

Mechanism of Natural Selection in Microbial Populations
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