Soru

In classical Roman jurisprudence, disputes regarding the ownership of transformed physical property were resolved through two competing doctrines: accession (*accessio*) and specification (*specificatio*). Under *accessio*, when an accessory material was inextricably conjoined to a principal physical object, title to the newly integrated whole vested entirely in the owner of the principal object, irrespective of the relative economic values of the constituent components. In contrast, *specificatio* governed instances where an artisan fashioned an entirely new species (*nova species*) from raw materials owned by another; the Sabinian school held that title remained with the supplier of the underlying substance, whereas the Proculian school maintained that title vested in the creator whose labor imparted the novel identity, provided the original material could not be restored to its pristine form.

Contemporary legal theorists evaluating property rights in synthetic genomics frequently invoke these classical paradigms to resolve disputes between bioresearchers who chemically synthesize novel genetic constructs and the custodians of indigenous biological specimens whose wild strains provided the underlying sequence templates. Applying *accessio* strictly to genetic engineering treats the proprietary molecular backbone into which genes are spliced as the principal entity, thereby extinguishing the property claims of the donors of the wild sequences once inserted. Conversely, applying the Proculian variant of *specificatio* awards unencumbered title to the bioengineer who creates a functionally distinct biological agent, provided that the raw donor sequence cannot be isolated back into its natural biological milieu without destroying the novel organism's engineered functionality. However, because contemporary patent regimes do not recognize physical reversibility as a criterion for intellectual property claims, judicial reliance on Roman property taxonomies creates an unresolved doctrinal friction between tangible chattel ownership and intangible informational rights.

Based on the passage, which of the following statements regarding the application of Roman property doctrines to biological engineering can be logically inferred? Select all that apply.