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Zorluk: ZorPharmacological Therapies

A practical nurse is preparing to administer an oral suspension to a client who weighs 154 lb154\text{ lb}. The healthcare provider has prescribed 15 mg/kg/day15\text{ mg/kg/day} to be administered in two equally divided doses. The pharmacy dispenses the medication with a concentration of 0.25 g/5 mL0.25\text{ g/5 mL}. How many mL\text{mL} should the practical nurse administer for each dose? Record your answer to the nearest tenth. Do not include units in your answer.

Cevap: 10.5 mL

Cevap

10.5
To arrive at the correct answer of 10.510.5, the practical nurse must systematically process multiple conversions. First, the client's weight is converted to kilograms (154÷2.2=70 kg154 \div 2.2 = 70\text{ kg}). Next, the total daily dose is calculated (70×15=1050 mg/day70 \times 15 = 1050\text{ mg/day}). Because the medication is divided into two equal doses, the single dose requirement is 525 mg525\text{ mg}. Before calculating the volume, the dispensed concentration of 0.25 g/5 mL0.25\text{ g/5 mL} must be converted to milligrams (0.25×1000=250 mg/5 mL0.25 \times 1000 = 250\text{ mg/5 mL}). Finally, using the desired over have formula: (525 mg÷250 mg)×5 mL(525\text{ mg} \div 250\text{ mg}) \times 5\text{ mL} equals exactly 10.5 mL10.5\text{ mL}.

Adım Adım Çözüm

1
Convert the client's weight from pounds to kilograms.
154 lb÷2.2 lb/kg=70 kg154\text{ lb} \div 2.2\text{ lb/kg} = 70\text{ kg}
Weight-based dosing requires the client's weight in kilograms.
2
Calculate the total daily dose in milligrams.
70 kg×15 mg/kg/day=1050 mg/day70\text{ kg} \times 15\text{ mg/kg/day} = 1050\text{ mg/day}
This establishes the total amount of medication the client needs over a 24-hour period.
3
Determine the amount required for a single dose.
1050 mg/day÷2 doses=525 mg/dose1050\text{ mg/day} \div 2\text{ doses} = 525\text{ mg/dose}
The prescription specifies two equally divided doses per day.
4
Convert the supplied medication concentration from grams to milligrams.
0.25 g×1000 mg/g=250 mg0.25\text{ g} \times 1000\text{ mg/g} = 250\text{ mg}. The available concentration is 250 mg250\text{ mg} per 5 mL5\text{ mL}.
Units of measurement must match between the desired dose (mg) and the available medication supply (g) before calculating volume.
5
Calculate the volume to administer for a single dose.
(525 mg÷250 mg)×5 mL=2.1×5 mL=10.5 mL(525\text{ mg} \div 250\text{ mg}) \times 5\text{ mL} = 2.1 \times 5\text{ mL} = 10.5\text{ mL}
Applying the standard dimensional analysis or 'Desired over Have times Volume' formula yields the exact volume to administer.

Anahtar Kavram

Multi-step dosage calculation involving weight conversion, frequency division, and unit conversion.
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