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Zorluk: Çok zorPharmacological Therapies

A practical nurse (PN) is preparing to administer a prescribed dose of cefdinir oral suspension to a pediatric client with acute otitis media. The client's weight is 27 pounds 8 ounces. The provider's prescription reads: cefdinir 14 mg/kg/day by mouth, divided in equal doses every 12 hours. The pharmacy supplies a bottle of cefdinir powder for oral suspension. The reconstitution instructions on the label state: "Add 38 mL of sterile water to the bottle to yield a final concentration of 125 mg/5 mL." How many milliliters (mL) should the PN administer for a single dose? (Record answer to the nearest tenth. Do not include units in answer.)

Cevap: 3.5 mL

Cevap

3.5
To determine the correct volume to administer, the nurse must execute four specific calculations. First, convert the weight of 27 pounds 8 ounces to kilograms (27.5 lbs÷2.2=12.5 kg27.5\text{ lbs} \div 2.2 = 12.5\text{ kg}). Second, calculate the total daily dose (12.5 kg×14 mg/kg/day=175 mg/day12.5\text{ kg} \times 14\text{ mg/kg/day} = 175\text{ mg/day}). Third, divide the daily dose by the frequency (every 12 hours = 2 doses per day; 175 mg÷2=87.5 mg/dose175\text{ mg} \div 2 = 87.5\text{ mg/dose}). Finally, use dimensional analysis with the reconstituted concentration (125 mg125\text{ mg} in 5 mL5\text{ mL}) to find the volume: (87.5 mg125 mg\frac{87.5\text{ mg}}{125\text{ mg}}) ×5 mL=3.5 mL\times 5\text{ mL} = 3.5\text{ mL}. The 38 mL38\text{ mL} of diluent is distractor information required only during the actual mixing process.

Adım Adım Çözüm

1
Convert the client's weight from pounds and ounces to kilograms.
12.5
Weight-based dosing requires the client's weight in kilograms. 88 ounces is 0.50.5 pounds (8÷168 \div 16), making the total weight 27.527.5 pounds. Dividing 27.527.5 by 2.22.2 yields 12.5 kg12.5\text{ kg}.
2
Calculate the total daily dose in milligrams.
175
Multiply the prescribed dose of 14 mg/kg/day14\text{ mg/kg/day} by the client's weight of 12.5 kg12.5\text{ kg} to get 175 mg/day175\text{ mg/day}.
3
Calculate the single dose amount.
87.5
The total daily dose is divided every 12 hours, which means 2 doses per day. 175 mg175\text{ mg} divided by 2 equals 87.5 mg87.5\text{ mg} per dose.
4
Calculate the volume of the single dose using the final concentration.
3.5
Using the final reconstituted concentration of 125 mg125\text{ mg} per 5 mL5\text{ mL}: 87.5 mg125 mg×5 mL=3.5 mL\frac{87.5\text{ mg}}{125\text{ mg}} \times 5\text{ mL} = 3.5\text{ mL}.

Anahtar Kavram

Pediatric Weight-Based Dosage Calculation with Reconstitution
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