A client recovering from an ischemic stroke is receiving continuous enteral nutrition via a percutaneous endoscopic gastrostomy (PEG) tube. The client's medication administration record includes scheduled morning doses of extended-release nifedipine and liquid acetaminophen. Which action by the practical nurse demonstrates safe pharmacological practice?
- ACrush the extended-release nifedipine into a fine powder, dissolve it in 30 mL of sterile water, and administer it via the PEG tube.
- Withhold the extended-release nifedipine, administer the liquid acetaminophen, and notify the registered nurse to request an appropriate immediate-release alternative.Cevap
- CSubstitute the oral nifedipine with an intravenous push antihypertensive medication to ensure the client receives the scheduled dose on time.
- DConvert the ordered nifedipine dosage into milligrams per kilogram (mg/kg) to determine if the capsule can be safely divided in half for administration.
Cevap
The safe action is to withhold the extended-release nifedipine, administer the liquid acetaminophen, and collaborate with the registered nurse to request a therapeutically equivalent immediate-release or liquid alternative.
Extended-release (ER) medications are formulated to release their active ingredients slowly over an extended period. They must never be crushed, chewed, or opened. Doing so destroys the delayed-release mechanism, causing a rapid absorption of the entire dose at once (dose dumping), which can lead to severe adverse effects such as profound hypotension. Because intact capsules cannot be given via a percutaneous endoscopic gastrostomy tube, the safest action is to withhold the medication, safely administer the liquid acetaminophen, and collaborate with the registered nurse or healthcare provider to obtain a therapeutically equivalent liquid or immediate-release formulation.
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Anahtar Kavram
Safe Administration of Enteral Tube Medications and Formulation Limitations
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