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Zorluk: ZorPharmacological Therapies

A pediatric client weighing 33 lb33 \text{ lb} is diagnosed with acute otitis media. The primary healthcare provider prescribes amoxicillin 80 mg/kg/day80 \text{ mg/kg/day} by mouth, to be administered in two equally divided doses. The pharmacy dispenses a powder for oral suspension with the manufacturer instructions: 'Reconstitute with 68 mL68 \text{ mL} of purified water to yield a final volume of 100 mL100 \text{ mL} and a concentration of 400 mg/5 mL400 \text{ mg}/5 \text{ mL}.' Based on this prescription, how many milliliters should the nurse administer for a single dose? (Record answer to the nearest tenth. Do not include units in answer.)

Cevap: 7.5 mL

Cevap

7.5
The correct dose is calculated by first converting the child's weight to kilograms (33 lb/2.2=15 kg33 \text{ lb} / 2.2 = 15 \text{ kg}). Next, the total daily dose is found by multiplying the weight by the prescribed rate (15 kg×80 mg/kg/day=1200 mg/day15 \text{ kg} \times 80 \text{ mg/kg/day} = 1200 \text{ mg/day}). Since the medication is divided into two doses, the single dose requirement is 600 mg600 \text{ mg}. Finally, using the supplied concentration of 400 mg400 \text{ mg} per 5 mL5 \text{ mL}, the required liquid volume is calculated as 600 mg×(5 mL/400 mg)=7.5 mL600 \text{ mg} \times (5 \text{ mL} / 400 \text{ mg}) = 7.5 \text{ mL}.

Adım Adım Çözüm

1
Convert the client's weight from pounds to kilograms.
15 kg15 \text{ kg}
The prescribed dosage is weight-based in mg/kg, so the weight must first be converted by dividing pounds by 2.2 (33÷2.2=1533 \div 2.2 = 15).
2
Calculate the total daily medication dose.
1200 mg/day1200 \text{ mg/day}
Multiply the client's weight in kilograms by the prescribed daily amount (15 kg×80 mg/kg/day=1200 mg/day15 \text{ kg} \times 80 \text{ mg/kg/day} = 1200 \text{ mg/day}).
3
Determine the required milligrams for a single dose.
600 mg/dose600 \text{ mg/dose}
The total daily dose is prescribed to be given in two equally divided doses, so it must be divided by 2 (1200 mg÷2=600 mg/dose1200 \text{ mg} \div 2 = 600 \text{ mg/dose}).
4
Calculate the liquid volume to administer per dose.
7.5 mL7.5 \text{ mL}
Use the final concentration ratio (400 mg/5 mL400 \text{ mg}/5 \text{ mL}) to find the volume: 600 mg×(5 mL/400 mg)=7.5 mL600 \text{ mg} \times (5 \text{ mL} / 400 \text{ mg}) = 7.5 \text{ mL}. The diluent volume (68 mL68 \text{ mL}) and total bottle volume (100 mL100 \text{ mL}) are distractor data points not used in calculating the individual dose.

Anahtar Kavram

Weight-based pediatric dosage calculation and filtering of extraneous reconstitution data.
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Pharmacological Therapies

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