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Zorluk: Çok zorPharmacological Therapies

During a pediatric clinic visit, a child weighing 37.4 lb37.4\text{ lb} is diagnosed with acute otitis media. The primary health care provider prescribes cefdinir oral suspension at the maximum recommended dosage of 14 mg/kg/day14\text{ mg/kg/day}, to be administered in equally divided doses every 12 hours12\text{ hours}. The clinic pharmacy dispenses a multi-dose bottle of cefdinir powder with the following label instructions: "Reconstitute by adding 38 mL38\text{ mL} of sterile water to yield 60 mL60\text{ mL} of oral suspension with a concentration of 250 mg/5 mL250\text{ mg}/5\text{ mL}."

The practical nurse is reinforcing medication administration instructions with the child's parents. How many milliliters (mL\text{mL}) should the nurse instruct the parents to administer for a single dose? (Record the answer to the nearest tenth. Do not include units in the answer.)

Cevap: 2.4

Cevap

2.4
To solve this, first convert pounds to kilograms: 37.4 lb÷2.2=17 kg37.4\text{ lb} \div 2.2 = 17\text{ kg}. Next, find the total daily dose: 17 kg×14 mg/kg/day=238 mg/day17\text{ kg} \times 14\text{ mg/kg/day} = 238\text{ mg/day}. Because it is given every 12 hours, divide by 2: 238÷2=119 mg/dose238 \div 2 = 119\text{ mg/dose}. Using the concentration of 250 mg250\text{ mg} in 5 mL5\text{ mL}, calculate the volume: (119 mg÷250 mg)×5 mL=2.38 mL(119\text{ mg} \div 250\text{ mg}) \times 5\text{ mL} = 2.38\text{ mL}. Finally, round to the nearest tenth to get 2.42.4.

Adım Adım Çözüm

1
Convert the client's weight from pounds to kilograms.
37.4 lb÷2.2 lb/kg=17 kg37.4\text{ lb} \div 2.2\text{ lb/kg} = 17\text{ kg}
Weight-based pediatric dosages require the weight to be in kilograms.
2
Calculate the total daily medication dosage.
17 kg×14 mg/kg/day=238 mg/day17\text{ kg} \times 14\text{ mg/kg/day} = 238\text{ mg/day}
The prescription is written as a daily total based on the child's weight.
3
Calculate the single dose amount.
238 mg/day÷2 doses/day=119 mg/dose238\text{ mg/day} \div 2\text{ doses/day} = 119\text{ mg/dose}
The medication is ordered every 12 hours, meaning the total daily amount must be divided into 2 equal doses.
4
Calculate the volume to administer for one dose using the final concentration.
119 mg250 mg×5 mL=2.38 mL\frac{119\text{ mg}}{250\text{ mg}} \times 5\text{ mL} = 2.38\text{ mL}
The concentration is 250 mg250\text{ mg} per 5 mL5\text{ mL}. The reconstitution water volume (38 mL38\text{ mL}) and total yield (60 mL60\text{ mL}) are distractors and not used in the formula.
5
Round the calculated volume to the nearest tenth as instructed.
2.382.38 rounds to 2.42.4
Standard rounding rules state that if the hundredths digit is 5 or greater, round up the tenths digit.

Anahtar Kavram

Advanced Pediatric Dosage Calculation and Reconstitution Interpretation
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