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Zorluk: ZorPharmacological Therapies

A practical nurse is preparing to administer a morning dose consisting of 5 units5\text{ units} of regular insulin and 15 units15\text{ units} of NPH insulin to a client with type 2 diabetes mellitus. After performing hand hygiene, in what order should the nurse perform the following actions to safely prepare the mixed injection? Arrange the steps in the correct chronological sequence.

  1. 1Roll the NPH insulin vial gently between the palms of the hands.
  2. 2Cleanse the rubber stoppers of both the regular and NPH insulin vials with alcohol swabs.
  3. 3Inject 15 units15\text{ units} of air into the NPH insulin vial without allowing the needle to touch the insulin.
  4. 4Inject 5 units5\text{ units} of air into the regular insulin vial and leave the needle in the vial.
  5. 5Invert the regular insulin vial and withdraw 5 units5\text{ units} of regular insulin.
  6. 6Insert the needle into the NPH insulin vial, invert it, and withdraw 15 units15\text{ units} of NPH insulin.

Cevap

The correct sequence is to first roll the NPH vial, then cleanse both vials, inject air into the NPH vial, inject air into the regular insulin vial, withdraw the regular insulin, and finally withdraw the NPH insulin.
The correct sequence for mixing insulins follows the 'Clear before Cloudy' principle. The nurse must first prepare the medication by rolling the NPH suspension and disinfecting the vials. Air must be injected into the cloudy vial first, followed by the clear vial, to pressurize them. The clear (regular) insulin is then withdrawn first to ensure no cloudy (NPH) insulin accidentally enters and contaminates the clear insulin vial.

Adım Adım Çözüm

1
Roll the NPH insulin vial gently between the palms.
The NPH suspension is evenly mixed.
NPH insulin settles and must be mixed gently to avoid bubbles that could lead to inaccurate dosing.
2
Cleanse the rubber stoppers of both vials.
The injection sites on the vials are disinfected.
Standard infection control practice dictates disinfecting vials prior to needle insertion.
3
Inject air into the NPH (cloudy) vial.
The NPH vial is pressurized without contaminating the needle.
Pressurizing the vial prevents a vacuum. Doing this first ensures the needle remains sterile for the regular insulin vial.
4
Inject air into the regular (clear) insulin vial.
The regular insulin vial is pressurized.
Pressurizing the vial prevents a vacuum and prepares it for immediate withdrawal.
5
Withdraw the regular (clear) insulin.
5 units5\text{ units} of clear insulin are drawn into the syringe.
Clear insulin must be drawn first ('clear before cloudy') to prevent NPH from accidentally contaminating the regular insulin vial.
6
Withdraw the NPH (cloudy) insulin.
15 units15\text{ units} of NPH are drawn into the syringe for a total volume of 20 units20\text{ units}.
The intermediate-acting insulin is drawn last to complete the mixed dose safely.

Anahtar Kavram

When mixing insulins, the regular (clear, short-acting) insulin must be drawn up before the NPH (cloudy, intermediate-acting) insulin to prevent contamination of the rapid-acting insulin.
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