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Zorluk: OrtaPharmacological Therapies

A practical nurse is caring for an adult client who weighs 143 lb143\text{ lb} and is prescribed cyclosporine oral solution. The prescribed dosage is 8 mg/kg/day8\text{ mg/kg/day} divided into two equal doses. The pharmacy dispenses cyclosporine oral solution 100 mg/mL100\text{ mg/mL}. How many mL should the nurse administer for one dose?

Record your answer using one decimal place. Do not include units in your answer.

Cevap: 2.6 mL

Cevap

The practical nurse should administer 2.6 mL per dose.
To determine the correct volume, the client's weight must first be converted to kilograms (143 lb÷2.2=65 kg143\text{ lb} \div 2.2 = 65\text{ kg}). The total daily dose is calculated by multiplying the weight by the prescribed rate (65 kg×8 mg/kg=520 mg/day65\text{ kg} \times 8\text{ mg/kg} = 520\text{ mg/day}). Because the medication is divided into two equal doses, the single dose is 260 mg260\text{ mg} (520 mg÷2520\text{ mg} \div 2). Finally, using the available concentration of 100 mg/mL100\text{ mg/mL}, the required volume is 2.6 mL2.6\text{ mL} (260 mg÷100 mg/mL260\text{ mg} \div 100\text{ mg/mL}).

Adım Adım Çözüm

1
Convert pounds to kilograms.
143 lb÷2.2=65 kg143\text{ lb} \div 2.2 = 65\text{ kg}.
The prescribed dose is weight-based in kg, so the client's weight must first be converted.
2
Calculate the total daily dose.
65 kg×8 mg/kg=520 mg/day65\text{ kg} \times 8\text{ mg/kg} = 520\text{ mg/day}.
To find the total amount of medication required for a 24-hour period.
3
Determine the single dose amount.
520 mg÷2 doses=260 mg/dose520\text{ mg} \div 2\text{ doses} = 260\text{ mg/dose}.
The prescription states the daily dose is divided into two equal doses.
4
Calculate the liquid volume to administer.
(260 mg÷100 mg)×1 mL=2.6 mL260\text{ mg} \div 100\text{ mg}) \times 1\text{ mL} = 2.6\text{ mL}.
To determine how many mL provide the required single dose of 260 mg using the available concentration.

Anahtar Kavram

Weight-based dosage calculation and administration of divided doses.
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