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Zorluk: ZorPharmacological Therapies

A pediatric client who weighs 28.6 lb28.6\text{ lb} is being treated for a severe bacterial infection. The primary health care provider prescribes oral amoxicillin at a dosage of 40 mg/kg/day40\text{ mg/kg/day} to be administered in equally divided doses every 8 hours8\text{ hours}. The medication bottle states a concentration of 250 mg/5 mL250\text{ mg}/5\text{ mL} after reconstitution. How many milliliters should the practical nurse administer for a single dose? (Record the answer to the nearest tenth. Do not include units in the answer.)

Cevap: 3.5 mL

Cevap

3.5
To solve this calculation, first convert pounds to kilograms: 28.6 lb÷2.2 lb/kg=13 kg28.6\text{ lb} \div 2.2\text{ lb/kg} = 13\text{ kg}. Next, determine the total daily dose: 13 kg×40 mg/kg/day=520 mg/day13\text{ kg} \times 40\text{ mg/kg/day} = 520\text{ mg/day}. Because the medication is prescribed every 8 hours, it is administered 3 times per 24 hours. The single dose is 520 mg÷3=173.33 mg/dose520\text{ mg} \div 3 = 173.33\text{ mg/dose}. Using the concentration of 250 mg250\text{ mg} per 5 mL5\text{ mL}, the volume to administer is (173.33 mg÷250 mg)×5 mL=3.466 mL(173.33\text{ mg} \div 250\text{ mg}) \times 5\text{ mL} = 3.466\text{ mL}. Rounding to the nearest tenth yields 3.5 mL3.5\text{ mL}.

Adım Adım Çözüm

1
Convert the client's weight from pounds to kilograms.
13 kg13\text{ kg}
The prescribed dosage is weight-based in mg/kg, so the weight must be in kilograms (28.6÷2.2=1328.6 \div 2.2 = 13).
2
Calculate the total daily dose of the medication.
520 mg/day520\text{ mg/day}
Multiply the client's weight in kg by the prescribed daily dosage (13×40=52013 \times 40 = 520).
3
Determine the amount of medication required for a single dose.
173.33 mg/dose173.33\text{ mg/dose}
The order states every 8 hours, which means 3 times a day (24 / 8 = 3). Divide the total daily dose by 3 (520÷3=173.333...520 \div 3 = 173.333...).
4
Calculate the volume needed for one dose and round to the nearest tenth.
3.5 mL3.5\text{ mL}
Use the available concentration (250 mg/5 mL250\text{ mg}/5\text{ mL}) to find the volume: (173.33÷250)×5=3.466 mL(173.33 \div 250) \times 5 = 3.466\text{ mL}. Rounding to the nearest tenth gives 3.53.5.

Anahtar Kavram

Weight-based pediatric dosage calculation and conversion
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