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Zorluk: ZorPharmacological Therapies

A practical nurse (PN) is preparing to administer a combined dose of regular insulin and NPH insulin in a single syringe to a client with type 2 diabetes mellitus. Arrange the following steps for preparing this medication in the correct chronological order.

  1. 1Roll the NPH insulin vial gently between the palms of the hands.
  2. 2Inject air equal to the prescribed dose into the NPH insulin vial.
  3. 3Inject air equal to the prescribed dose into the regular insulin vial.
  4. 4Withdraw the prescribed dose of regular insulin into the syringe.
  5. 5Withdraw the prescribed dose of NPH insulin into the syringe.

Cevap

The correct sequence is to roll the NPH vial, inject air into the NPH vial, inject air into the regular insulin vial, withdraw the regular insulin, and finally withdraw the NPH insulin.
The correct sequence for mixing insulins ensures precise dosing and prevents contamination of the vials. The PN must first gently roll the NPH (cloudy) insulin to resuspend the particles. To prevent negative pressure, air is injected into the NPH vial first, followed by injecting air into the regular (clear) insulin vial. The regular insulin is drawn up immediately after injecting air into its vial (clear before cloudy). Finally, the NPH insulin is drawn up. This sequence prevents the intermediate-acting NPH insulin from accidentally entering and altering the pharmacokinetics of the rapid/short-acting regular insulin vial.

Adım Adım Çözüm

1
Roll the NPH insulin vial gently between the palms.
The NPH insulin suspension is evenly mixed without creating air bubbles.
NPH insulin is a suspension that settles on standing and requires gentle mixing prior to use to ensure accurate dosing.
2
Inject air equal to the prescribed dose into the NPH insulin vial.
The NPH vial is pressurized.
Prevents negative pressure in the vial. Doing this first keeps the needle free of regular insulin, preventing contamination of the NPH vial.
3
Inject air equal to the prescribed dose into the regular insulin vial.
The regular insulin vial is pressurized and ready for withdrawal.
Prevents negative pressure. Because the needle is now in the regular insulin vial, withdrawal can begin immediately without removing the needle.
4
Withdraw the prescribed dose of regular insulin into the syringe.
Clear insulin is drawn into the syringe.
Regular (clear) insulin is always drawn up first. This prevents contamination of the rapid-acting insulin vial with the longer-acting NPH insulin.
5
Withdraw the prescribed dose of NPH insulin into the syringe.
The mixed dose is completed accurately.
NPH (cloudy) insulin is drawn last because introducing regular insulin into the NPH vial does not negatively alter the intermediate-acting insulin's properties.

Anahtar Kavram

Safe preparation and mixing of regular (clear) and NPH (cloudy) insulins
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