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Zorluk: ZorPharmacological Therapies

A healthcare provider prescribes ceftriaxone 50 mg/kg/day50\text{ mg/kg/day} intramuscularly (IM) to be given in two divided doses for a toddler who weighs 26.4 lbs26.4\text{ lbs}. The pharmacy supplies ceftriaxone as a powder in a vial labeled 1 g1\text{ g}. The reconstitution instructions on the vial state: "Add 2.1 mL2.1\text{ mL} of sterile water for injection to yield a final concentration of 350 mg/mL350\text{ mg/mL}."

How many milliliters (mL\text{mL}) should the practical nurse administer for one dose? Record your answer to the nearest tenth. Do not include units in your answer.

Cevap: 0.9 mL

Cevap

0.9
To determine the correct volume to administer, first convert the weight to kilograms (26.4 lbs÷2.2=12 kg26.4\text{ lbs} \div 2.2 = 12\text{ kg}). Next, calculate the total daily dose by multiplying the weight by the prescribed rate (12 kg×50 mg/kg=600 mg12\text{ kg} \times 50\text{ mg/kg} = 600\text{ mg}). Because the medication is given in two divided doses, divide the total daily dose by 2 (600 mg÷2=300 mg600\text{ mg} \div 2 = 300\text{ mg}). Finally, use the reconstituted concentration of 350 mg/mL350\text{ mg/mL} to find the volume: (300 mg÷350 mg/mL=0.857... mL300\text{ mg} \div 350\text{ mg/mL} = 0.857...\text{ mL}). Rounding to the nearest tenth yields 0.9 mL0.9\text{ mL}.

Adım Adım Çözüm

1
Convert the client's weight from pounds to kilograms.
26.4 lbs÷2.2 lbs/kg=12 kg26.4\text{ lbs} \div 2.2\text{ lbs/kg} = 12\text{ kg}
The medication dosage is prescribed based on the client's weight in kilograms.
2
Calculate the total daily dosage in milligrams.
12 kg×50 mg/kg/day=600 mg/day12\text{ kg} \times 50\text{ mg/kg/day} = 600\text{ mg/day}
This establishes the total amount of medication the toddler needs over a 24-hour period.
3
Determine the required milligrams for a single dose.
600 mg/day÷2 doses=300 mg/dose600\text{ mg/day} \div 2\text{ doses} = 300\text{ mg/dose}
The prescription states the medication is to be given in two divided doses per day, and the question asks for the volume of one dose.
4
Calculate the volume of the medication to administer based on the reconstituted concentration.
300 mg÷350 mg/mL=0.85714... mL300\text{ mg} \div 350\text{ mg/mL} = 0.85714...\text{ mL}
The final concentration yield (350 mg/mL350\text{ mg/mL}), not the diluent volume, must be used to calculate the physical volume to draw up into the syringe.
5
Round the final answer to the nearest tenth.
0.9 mL0.9\text{ mL}
The question explicitly asks to record the answer to the nearest tenth.

Anahtar Kavram

Weight-based pediatric dosage calculation and medication reconstitution
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