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Zorluk: OrtaPharmacological and Parenteral Therapies

A healthcare provider orders intermittent intravenous ceftriaxone for an adult client diagnosed with community-acquired pneumonia. The client's only vascular access is a peripheral catheter currently infusing lactated Ringer's solution at 100 mL/hr. What is the safest action by the nurse regarding the administration of this antibiotic?

  1. A
    Connect the antibiotic tubing to the Y-site port above the infusion pump while the primary fluid continues running.
  2. B
    Pause the primary fluid, infuse the antibiotic as a secondary piggyback, and immediately resume the primary fluid.
  3. Halt the continuous infusion, flush the line with normal saline, infuse the antibiotic, and flush the line again.Cevap
  4. D
    Withhold the medication and contact the healthcare provider to request changing the primary fluid to normal saline.

Cevap

The safest action is to halt the continuous infusion of lactated Ringer's, flush the line with normal saline, infuse the antibiotic, and then flush the line again before restarting the primary fluid.
Ceftriaxone binds chemically with calcium to form a particulate precipitate that can lead to fatal organ damage, particularly in the lungs or kidneys. Because lactated Ringer's solution contains calcium, the two fluids are highly incompatible. When a client has a single IV access site, the standard and safest nursing practice is to pause the incompatible continuous fluid, completely flush the tubing with a neutral, compatible solution (like 0.9% sodium chloride), infuse the medication, and then flush the line again before restarting the primary fluid.

Adım Adım Çözüm

1
Verify the compatibility of the prescribed antibiotic (ceftriaxone) with the current continuous IV fluid (lactated Ringer's solution).
Identify that ceftriaxone is incompatible with lactated Ringer's.
Lactated Ringer's contains calcium. Ceftriaxone binds with calcium to form a dangerous, solid precipitate that can cause fatal organ damage.
2
Determine the best procedural intervention for administering an incompatible medication through a single IV access site.
Select the Saline-Administer-Saline (SAS) flush method.
The nurse must clear the IV tubing of the incompatible fluid to ensure the two substances never mix in the line.
3
Execute the administration protocol.
Pause the pump, flush thoroughly with 0.9% sodium chloride, infuse the ceftriaxone, flush again with 0.9% sodium chloride, and restart the pump.
This guarantees that the antibiotic reaches the bloodstream safely without interacting with the calcium-containing primary fluid.

Anahtar Kavram

Ceftriaxone is contraindicated for concurrent administration with calcium-containing intravenous solutions due to the risk of precipitate formation. When managing incompatible medications in a single line, the tubing must be thoroughly flushed with a compatible solution before and after administration.
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