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Zorluk: OrtaPharmacological and Parenteral Therapies

A nurse is reviewing a new medication order for a pediatric client who weighs 20 kg20\text{ kg}. The healthcare provider has prescribed oral amoxicillin 400 mg400\text{ mg} every 8 hours8\text{ hours} for an infection. The pharmacy reference states that the safe pediatric dosage range is 20 to 40 mg/kg/day20\text{ to }40\text{ mg/kg/day} administered in equally divided doses every 8 hours8\text{ hours}. Based on this information, which of the following is the most appropriate action by the nurse?

  1. Withhold the medication and contact the healthcare provider because the prescribed dose exceeds the safe maximum daily limit.Cevap
  2. B
    Administer the medication as prescribed because the single dose of 400 mg400\text{ mg} matches the minimum safe daily dose.
  3. C
    Give the medication as ordered because the total daily dose of 1200 mg1200\text{ mg} falls safely within the therapeutic range.
  4. D
    Administer the first dose to prevent delaying infection treatment, then notify the provider to adjust the remaining doses.

Cevap

The nurse must withhold the medication and contact the healthcare provider because the prescribed dose exceeds the safe maximum daily limit.
The prescribed dosage results in a total daily dose of 1200 mg1200\text{ mg} (400 mg400\text{ mg} administered 33 times a day). The safe maximum daily limit for a 20 kg20\text{ kg} child is 800 mg800\text{ mg} (40 mg/kg×20 kg40\text{ mg/kg} \times 20\text{ kg}). Because the order exceeds the safe limit, the nurse is required to hold the medication and clarify the order with the prescribing provider to prevent potential toxicity.

Adım Adım Çözüm

1
Determine the safe daily dosage range based on the client's weight.
Minimum: 20 kg×20 mg/kg/day=400 mg/day20\text{ kg} \times 20\text{ mg/kg/day} = 400\text{ mg/day}. Maximum: 20 kg×40 mg/kg/day=800 mg/day20\text{ kg} \times 40\text{ mg/kg/day} = 800\text{ mg/day}.
Weight-based calculations establish the therapeutic window to prevent toxicity.
2
Calculate the total prescribed daily dose.
The medication is prescribed every 8 hours8\text{ hours}, which equates to 33 doses in a 24-hour24\text{-hour} period. 400 mg/dose×3 doses/day=1200 mg/day400\text{ mg/dose} \times 3\text{ doses/day} = 1200\text{ mg/day}.
Comparing apples to apples requires calculating the total amount the client will receive over 24 hours.
3
Compare the prescribed daily dose to the safe range.
The ordered dose of 1200 mg/day1200\text{ mg/day} is significantly greater than the maximum safe limit of 800 mg/day800\text{ mg/day}.
Identifying that the dose falls outside the safe parameters is critical for preventing an adverse drug event.
4
Determine the priority nursing action.
The nurse must withhold the medication and immediately contact the prescribing healthcare provider for an order revision.
Nurses have a legal and ethical duty to intercept medication errors and never administer a dose known to be toxic.

Anahtar Kavram

Pediatric Dosage Calculation and Medication Safety
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