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Zorluk: ZorPharmacological and Parenteral Therapies

A nurse in the intensive care unit is caring for a client with a hypertensive emergency. The client weighs 198 lb198\text{ lb}. The client is currently receiving a continuous intravenous (IV) infusion of nitroprusside at 14 mL/hr14\text{ mL/hr}. The IV solution contains 50 mg50\text{ mg} of nitroprusside in 250 mL250\text{ mL} of 5%5\% dextrose in water (D5WD_5W). Based on the client's current blood pressure of 185/110 mm Hg185/110\text{ mm Hg}, the healthcare provider prescribes an increase in the nitroprusside infusion rate by 0.5 mcg/kg/min0.5\text{ mcg/kg/min}. What is the new infusion rate in mL/hr\text{mL/hr} that the nurse should set on the IV pump? Record your answer using one decimal place.

Cevap: 27.5 mL/hr

Cevap

27.5
To determine the new infusion rate, calculate the volume required for the prescribed increase and add it to the current baseline rate. First, convert the weight: 198 lb÷2.2=90 kg198\text{ lb} \div 2.2 = 90\text{ kg}. Calculate the increase per minute: 0.5 mcg/kg/min×90 kg=45 mcg/min0.5\text{ mcg/kg/min} \times 90\text{ kg} = 45\text{ mcg/min}. Convert to an hourly dose: 45 mcg/min×60 min/hr=2700 mcg/hr45\text{ mcg/min} \times 60\text{ min/hr} = 2700\text{ mcg/hr}. Next, determine the concentration of the available solution: 50 mg=50,000 mcg50\text{ mg} = 50,000\text{ mcg}; 50,000 mcg÷250 mL=200 mcg/mL50,000\text{ mcg} \div 250\text{ mL} = 200\text{ mcg/mL}. Divide the hourly dose increase by the concentration: 2700 mcg/hr÷200 mcg/mL=13.5 mL/hr2700\text{ mcg/hr} \div 200\text{ mcg/mL} = 13.5\text{ mL/hr}. Finally, add this volume increase to the current rate: 14 mL/hr+13.5 mL/hr=27.5 mL/hr14\text{ mL/hr} + 13.5\text{ mL/hr} = 27.5\text{ mL/hr}.

Adım Adım Çözüm

1
Convert the client's weight to kilograms.
90 kg
The prescribed dose increase is weight-based (mcg/kg/min), so weight must be in kg.
2
Calculate the total mcg/min required for the rate increase.
45 mcg/min
Multiplies the prescribed dose increase (0.5 mcg/kg/min) by the patient's weight (90 kg).
3
Convert the required dose increase from mcg/min to mcg/hr.
2700 mcg/hr
The IV infusion pump is programmed in mL/hr, so the dose must be standardized to an hourly rate.
4
Determine the concentration of the IV solution in mcg/mL.
200 mcg/mL
Converts 50 mg to 50,000 mcg, then divides by the total volume (250 mL) to find the amount of drug per mL.
5
Calculate the additional infusion rate (mL/hr) required for the increase.
13.5 mL/hr
Divides the required hourly dose increase (2700 mcg/hr) by the drug concentration (200 mcg/mL).
6
Calculate the new total infusion rate.
27.5 mL/hr
Adds the required increase (13.5 mL/hr) to the current continuous infusion rate (14 mL/hr).

Anahtar Kavram

Complex weight-based IV medication titration and dosage calculation
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