Soru

Zorluk: Çok zorPharmacological and Parenteral Therapies

A critical care nurse is managing a client with severe sepsis. The client is receiving a continuous intravenous infusion of norepinephrine.

Client Data:
- Weight: 220220 lb
- Current mean arterial pressure (MAP): 5454 mm Hg
- Current infusion pump rate: 1818 mL/hr
- Medication concentration: Norepinephrine 88 mg in 250250 mL 5%5\% Dextrose in Water (D5W)
- Provider titration protocol: "Increase norepinephrine by 0.040.04 mcg/kg/min every 55 minutes until MAP is ≥65\geq 65 mm Hg."

The nurse determines the need to increase the infusion rate according to the protocol. What should be the newly programmed infusion pump rate in mL/hr?

*Round the final answer to the nearest tenth.*

Cevap: 25.5 mL/hr

Cevap

The new infusion pump rate should be set to 25.5 mL/hr.
To find the new pump rate, the nurse must first determine how much extra volume per hour is needed to satisfy the 0.040.04 mcg/kg/min increase. By converting the client's weight to 100100 kg, the required dose increase is 44 mcg/min, which equals 240240 mcg/hr. Using the bag concentration of 3232 mcg/mL, the required volume increase is 7.57.5 mL/hr. Adding this to the baseline rate of 1818 mL/hr yields the final correct rate of 25.525.5 mL/hr.

Adım Adım Çözüm

1
Convert weight to kilograms.
220220 lb / 2.22.2 = 100100 kg.
Weight-based dosing requires the client's weight in kg.
2
Calculate the dose increment per minute.
0.040.04 mcg/kg/min * 100100 kg = 44 mcg/min.
This determines how much additional medication the client needs every minute based on the protocol.
3
Convert the dose increment to an hourly rate.
44 mcg/min * 6060 min/hr = 240240 mcg/hr.
Infusion pumps are programmed in mL/hr, so the dose must be expressed per hour.
4
Determine the concentration of the IV bag in mcg/mL.
88 mg = 80008000 mcg. 80008000 mcg / 250250 mL = 3232 mcg/mL.
Medication is ordered in mcg, but supplied in mg. Both units must match to find the volume.
5
Calculate the volume increment in mL/hr.
240240 mcg/hr / 3232 mcg/mL = 7.57.5 mL/hr.
This isolates the exact amount of fluid needed to deliver the required increase in medication.
6
Add the volume increment to the current infusion rate.
1818 mL/hr + 7.57.5 mL/hr = 25.525.5 mL/hr.
The protocol requires increasing the current rate, not replacing it with only the increment.

Anahtar Kavram

Advanced medication titration requires calculating the incremental dose increase based on weight and concentration, then accurately adding that newly calculated volume rate to the baseline continuous infusion rate.
Bu soruyu puanla