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Zorluk: Çok zorPhysiological Adaptation

A client with acute kidney injury is exhibiting profound muscle weakness. The bedside cardiac monitor suddenly displays a widened QRS complex and tall, peaked T waves. The laboratory reports a stat serum potassium level of 7.8 mEq/L7.8\text{ mEq/L}. The healthcare provider has prescribed several urgent interventions. Arrange the following pharmacological actions in the priority sequence the nurse must implement them.

  1. 1Administer intravenous calcium gluconate.
  2. 2Administer intravenous regular insulin concurrently with 50% dextrose.
  3. 3Administer sodium polystyrene sulfonate via retention enema.
  4. 4Obtain a follow-up serum potassium level.

Cevap

The correct priority sequence is to first stabilize the myocardium with calcium gluconate, second shift potassium intracellularly with insulin and dextrose, third remove potassium from the body with sodium polystyrene sulfonate, and finally evaluate the client's response with follow-up laboratory tests.
The pathophysiology of severe hyperkalemia demands a specific sequence of interventions. The most immediate threat to life is cardiac toxicity, manifested by widened QRS complexes and peaked T waves. Therefore, calcium gluconate is always the first line of treatment to raise the threshold potential and stabilize the myocardium. Next, fast-acting agents like IV insulin and dextrose are used to rapidly shift potassium into cells. Slower-acting agents like sodium polystyrene sulfonate are then given for definitive removal from the body. Finally, evaluation of the therapy is required.

Adım Adım Çözüm

1
Administer intravenous calcium gluconate.
Myocardial excitability is decreased and the cell membrane is stabilized.
This is the immediate life-saving intervention to prevent lethal ventricular arrhythmias caused by severe hyperkalemia.
2
Administer intravenous regular insulin concurrently with 50% dextrose.
Potassium is rapidly driven from the intravascular space into the intracellular fluid.
This provides a rapid, albeit temporary, reduction in the circulating serum potassium level, buying time for excretion therapies to work.
3
Administer sodium polystyrene sulfonate via retention enema.
Potassium is exchanged for sodium in the large intestine and excreted in feces.
This provides permanent removal of potassium from the body, but is given after stabilizing medications because its onset of action takes hours.
4
Obtain a follow-up serum potassium level.
Current serum electrolyte status is documented.
The nurse must evaluate if the applied medical therapies were effective or if further interventions, such as emergent hemodialysis, are required.

Anahtar Kavram

In the presence of hyperkalemia with ECG changes, immediate myocardial stabilization with calcium gluconate must precede therapies that lower serum potassium.
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